LINF_240014300

DNA replication licensing factor MCM5 - putative
Leishmania infantum JPCM5 OG6: OG6_102165 OG7: OG7_0001163 105 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 105 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_280030800 ⚠
DNA replication licensing factor MCM6 - putat
— +18 more Both
LINF_320036900 ⚠
DNA replication licensing factor MCM7 - putat
— +18 more Both
LINF_090008100 ⚠
DNA replication licensing factor MCM4 - puta
— +18 more Both
LINF_050008300 ⚠
DNA replication licensing factor MCM8 - putat
— +18 more Both
LINF_330036300 ⚠
DNA replication licensing factor MCM3 - putat
— +18 more Both
LINF_280014100 ⚠
DNA replication licensing factor MCM2 - putat
— +18 more Both
LINF_350054700 ⚠
DNA replication licensing factor MCM9 - putat
— +17 more OG7
LINF_360035800 ⚠
Flagellar Member 1
— OG7
LINF_260011000 ⚠
hypothetical protein - conserved
— OG7
LINF_310034600 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LINF_360032400 ⚠
chromatin assembly factor 1 subunit b-like pr
— OG7
LINF_340048700 ⚠
GRIP domain containing protein - putative
— OG7
LINF_360059000 ⚠
2OG-Fe(II) oxygenase superfamily - putative
— OG7
LINF_310018600 ⚠
Protein of unknown function (DUF3638)/Protein
— OG7
LINF_340051500 ⚠
phosphatidylinositol 3-kinase (tor2) - putati
— OG7
LINF_310026800 ⚠
ubiquitin-fusion protein
— OG7
LINF_110007500 ⚠
hypothetical protein - conserved
— OG7
LINF_250015200 ⚠
hypothetical protein - conserved
— OG7
LINF_290007600 ⚠
Tubulin-tyrosine ligase family - putative
— OG7
LINF_320036500 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_300028200 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_350054800 ⚠
tubulin tyrosine ligase - putative
— OG7
LINF_180008700 ⚠
tubulin tyrosine ligase protein - putative
— OG7
LINF_110008900 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LINF_270033100 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_160008900 ⚠
tubulin tyrosine ligase - putative
— OG7
LINF_200012800 ⚠
tubulin-tyrosine ligase - putative
— OG7
LINF_220022600 ⚠
CCR4 associated factor - putative
— OG7
LINF_250018900 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LINF_360031500 ⚠
Cullin protein neddylation domain containing
— OG7
LINF_360038700 ⚠
cullin-like protein
— OG7
LINF_160012000 ⚠
hypothetical protein - conserved
— OG7
LINF_360051100 ⚠
GINS complex protein - putative
— Both
LINF_070011000 ⚠
hypothetical protein - conserved
— OG7
LINF_110009600 ⚠
pumillio protein 10 - putative
— OG7
LINF_140011200 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_040010500 ⚠
Tetratricopeptide repeat/TPR repeat - putativ
— OG7
LINF_090015800 ⚠
SLA/LP autoantigen-like protein
— OG7
LINF_250021400 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
LINF_040006300 ⚠
exosome complex exonuclease RRP40 - putative
— OG7
LINF_180010700 ⚠
Flagellar-associated PapD-like - putative
— OG7
LINF_180013500 ⚠
Periodic tryptophan protein 2 homolog - putat
— OG7
LINF_240027200 ⚠
hypothetical protein - conserved
— OG7
LINF_110008600 ⚠
hypothetical protein - conserved
— OG7
LINF_230026400 ⚠
neutral sphingomyelinase activation associate
— OG7
LINF_330037100 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LINF_160019300 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LINF_310034200 ⚠
RNA polymerase ii largest subunit
— OG7
LINF_160018000 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LINF_280027800 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.