LINF_220022600

CCR4 associated factor - putative
Leishmania infantum JPCM5 OG6: OG6_101138 OG7: OG7_0005422 146 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 146 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_210013800
Domain of unknown function (DUF3819)/CCR4-Not
— Both
LINF_250025200
Not1 N-terminal domain - CCR4-Not complex com
— Both
LINF_230005100
hypothetical protein - conserved
— Both
LINF_120008600
CCR4-NOT transcription complex subunit 2 - pu
— Both
LINF_340051700
cell differentiation protein-like protein
— Both
LINF_270006400
hypothetical protein - conserved
— OG6
LINF_080005000 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LINF_360070900
CCR4-NOT transcription complex subunit 10 - p
— Both
LINF_190011800 ⚠
kinesin - putative
— OG6
LINF_160019300 ⚠
DNA-directed rna polymerase I largest subunit
— Both
LINF_190011700 ⚠
kinesin - putative
— OG6
LINF_150015800
hypothetical protein - conserved
— Both
LINF_220022200
hypothetical protein - conserved
— Both
LINF_140011200
WD domain - G-beta repeat - putative
— Both
LINF_120011300 ⚠
Tetratricopeptide repeat/TPR repeat - putativ
— Both
LINF_160008900 ⚠
tubulin tyrosine ligase - putative
— Both
LINF_060017400
hypothetical protein - conserved
— Both
LINF_090019500
AAA family ATPase - putative
— Both
LINF_300027300
RNA-binding protein - putative
— OG6
LINF_050016100 ⚠
Phosphatidylinositol 4-phosphate 5-kinase - p
— OG7
LINF_340029900 ⚠
Sec7 domain containing protein - putative
— OG7
LINF_340031100 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LINF_300016500 ⚠
WW domain containing protein - putative
— OG7
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_300014700 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_160017100 ⚠
WW domain containing protein - putative
— OG7
LINF_050009100 ⚠
Tetratricopeptide repeat/TPR repeat - putativ
— OG7
LINF_290007600 ⚠
Tubulin-tyrosine ligase family - putative
— OG7
LINF_320036500 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_300028200 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_350054800 ⚠
tubulin tyrosine ligase - putative
— OG7
LINF_180008700 ⚠
tubulin tyrosine ligase protein - putative
— OG7
LINF_110008900 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LINF_270033100 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_200012800 ⚠
tubulin-tyrosine ligase - putative
— OG7
LINF_300039400
hypothetical protein - conserved
— OG7
LINF_090008100 ⚠
DNA replication licensing factor MCM4 - puta
— OG7
LINF_330036300 ⚠
DNA replication licensing factor MCM3 - putat
— OG7
LINF_320020300 ⚠
phosphatidylinositol 3-related kinase - putat
— OG7
LINF_340051500 ⚠
phosphatidylinositol 3-kinase (tor2) - putati
— OG7
LINF_360031500 ⚠
Cullin protein neddylation domain containing
— OG7
LINF_360038700 ⚠
cullin-like protein
— OG7
LINF_130020100 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_020006200 ⚠
phosphatidylinositol kinase related protein -
— OG7
LINF_310034600 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LINF_360023600 ⚠
neurobeachin/beige protein - putative
— OG7
LINF_310006600 ⚠
DNA-directed RNA polymerase II subunit 2 - pu
— OG7
LINF_280027800 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LINF_160018000 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LINF_050009000 ⚠
structural maintenance of chromosome (SMC) -
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.