LINF_210013800

Domain of unknown function (DUF3819)/CCR4-Not complex component - Not1 - putative
Leishmania infantum JPCM5 OG6: OG6_101511 OG7: OG7_0005420 97 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 97 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_120008600
CCR4-NOT transcription complex subunit 2 - pu
— +2 more Both
LINF_220022600
CCR4 associated factor - putative
— Both
LINF_340051700
cell differentiation protein-like protein
— Both
LINF_250025200
Not1 N-terminal domain - CCR4-Not complex com
— Both
LINF_100017900
Eukaryotic translation initiation factor 4 ga
— Both
LINF_320020300 ⚠
phosphatidylinositol 3-related kinase - putat
— OG7
LINF_340047100 ⚠
target of rapamycin kinase 3
— OG7
LINF_200016300 ⚠
phosphatidylinositol 3-kinase - putative
— OG7
LINF_180009600 ⚠
tubulin-specific chaperone - putative
— OG7
LINF_160017100 ⚠
WW domain containing protein - putative
— OG7
LINF_300014700 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_300016500 ⚠
WW domain containing protein - putative
— OG7
LINF_340031100 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LINF_340029900 ⚠
Sec7 domain containing protein - putative
— OG7
LINF_100016600 ⚠
Translation initiation factor eIF-2B subunit
— OG7
LINF_270018500 ⚠
translation initiation factor eIF2B delta sub
— OG7
LINF_090019500
AAA family ATPase - putative
— Both
LINF_170018800 ⚠
5'-3' exoribonuclease B - putative
— OG7
LINF_120005000 ⚠
translation initiation factor EIF-2b alpha su
— Both
LINF_140015400
tc40 antigen-like
— Both
LINF_190011700 ⚠
kinesin - putative
— OG6
LINF_190011800 ⚠
kinesin - putative
— OG6
LINF_360081200
Ribosomal protein L1p/L10e family - putative
— Both
LINF_040012000
Axonemal dynein light chain - putative
— Both
LINF_200007600
Midasin - putative
— Both
LINF_020006200 ⚠
phosphatidylinositol kinase related protein -
— Both
LINF_110010500
mRNA cap guanine-N7 methyltransferase - putat
— Both
LINF_350040500 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LINF_160021600 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_130020100 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_330019400 ⚠
Axonemal inner arm dynein light chain - putat
— OG7
LINF_210017800 ⚠
dynein arm light chain - putative
— OG7
LINF_330040400 ⚠
46 kD virulence factor
— OG7
LINF_240013500 ⚠
hypothetical protein
— OG7
LINF_210024900 ⚠
Microtubule-binding protein MIP-T3 - putative
— OG7
LINF_130006500 ⚠
protein kinase A regulatory subunit
— OG7
LINF_320046900 ⚠
cAMP response protein 1 - putative
— OG7
LINF_340035100 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LINF_080005000 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LINF_360037400 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LINF_330016300 ⚠
dnaj chaperone-like protein
— OG7
LINF_220005800 ⚠
heat shock protein DNAJ - putative
— OG7
LINF_350035100 ⚠
chaperone protein DNAj - putative
— OG7
LINF_320040500 ⚠
chaperone protein DNAj - putative
— OG7
LINF_360028100 ⚠
chaperone protein DNAj - putative
— OG7
LINF_040012900 ⚠
heat shock protein - putative
— OG7
LINF_250017100 ⚠
DNAj-like protein
— OG7
LINF_150019800 ⚠
DnaJ domain/DnaJ central domain containing pr
— OG7
LINF_260024800 ⚠
microtubule-associated protein - putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.