LINF_340047100

target of rapamycin kinase 3
Leishmania infantum JPCM5 OG6: OG6_138996 OG7: OG7_0001934 317 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 317 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_290025700 ⚠
dihydrolipoamide dehydrogenase - putative
— OG7
LINF_330023100 ⚠
hypothetical protein - conserved
— Both
LINF_310034500 ⚠
2-oxoglutarate dehydrogenase - e3 component -
— +1 more Both
LINF_310034600 ⚠
acetoin dehydrogenase e3 component-like prote
— Both
LINF_320035600 ⚠
CS domain/TPR repeat/Tetratricopeptide repeat
— Both
LINF_360061900 ⚠
glycosyl hydrolase - putative
— Both
LINF_060011400 ⚠
60S ribosomal protein L23a - putative
— OG7
LINF_140018100 ⚠
ras-like small GTPases - putative
— OG7
LINF_260017600 ⚠
hypothetical protein - conserved
— OG7
LINF_050014100 ⚠
CPSF A subunit region containing protein - pu
— OG7
LINF_190015000 ⚠
FYVE zinc finger containing protein - putativ
— OG7
LINF_300042900 ⚠
CPSF-domain protein - putative
— OG7
LINF_350040400 ⚠
zinc finger protein - putative
— OG7
LINF_310007500 ⚠
TPR/MLP1/MLP2-like protein - putative
— OG7
LINF_340035700 ⚠
ribosomal protein L3 - putative
— OG7
LINF_320038800 ⚠
ribosomal protein L3 - putative
— OG7
LINF_340035600 ⚠
ribosomal protein L3 - putative
— OG7
LINF_300039100 ⚠
60S ribosomal protein L9 - putative
— OG7
LINF_210018100 ⚠
60S ribosomal protein L9 - putative
— OG7
LINF_280020500 ⚠
Cell division control protein 48 - putative
— OG7
LINF_260009900 ⚠
DNA polymerase sigma-like protein
— OG7
LINF_360049000 ⚠
hypothetical protein
— OG7
LINF_070012600 ⚠
topoisomerase-related function protein-like p
— OG7
LINF_230023100 ⚠
DNA polymerase theta (helicase domain only) -
— OG7
LINF_170016300 ⚠
ATP-dependent RNA helicase - putative
— OG7
LINF_320019700 ⚠
ATP-dependent DNA DEAD/DEAH box helicase - pu
— OG7
LINF_130009900 ⚠
ATP-dependent RNA helicase - putative
— OG7
LINF_360023600 ⚠
neurobeachin/beige protein - putative
— OG7
LINF_340008700 ⚠
DNA-directed RNA polymerase III subunit C1 -
— OG7
LINF_310034200 ⚠
RNA polymerase ii largest subunit
— OG7
LINF_330037100 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LINF_230026400 ⚠
neutral sphingomyelinase activation associate
— OG7
LINF_150015800 ⚠
hypothetical protein - conserved
— OG7
LINF_340014400 ⚠
60S ribosomal protein L13a - putative
— OG7
LINF_150007100 ⚠
60S ribosomal protein L13a - putative
— OG7
LINF_300010000 ⚠
hypothetical protein - conserved
— OG7
LINF_160018000 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LINF_280027800 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LINF_240029100 ⚠
cullin-like protein-like protein
— OG7
LINF_360038700 ⚠
cullin-like protein
— OG7
LINF_360031500 ⚠
Cullin protein neddylation domain containing
— OG7
LINF_190014600 ⚠
CAP-Gly domain containing protein - putative
— OG7
LINF_180009600 ⚠
tubulin-specific chaperone - putative
— OG7
LINF_170010600 ⚠
hypothetical protein - conserved
— OG7
LINF_040012000 ⚠
Axonemal dynein light chain - putative
— OG7
LINF_280030800 ⚠
DNA replication licensing factor MCM6 - putat
— OG7
LINF_350054700 ⚠
DNA replication licensing factor MCM9 - putat
— OG7
LINF_320020400 ⚠
Microtubule-binding protein MIP-T3 - putative
— OG7
LINF_130007600 ⚠
hypothetical protein - conserved
— OG7
LINF_350024000 ⚠
ribosomal protein L15 - putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.