LINF_070012600

topoisomerase-related function protein-like protein
Leishmania infantum JPCM5 OG6: OG6_101092 OG7: OG7_0003906 48 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 48 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_020006200 ⚠
phosphatidylinositol kinase related protein -
— OG7
LINF_260012300 ⚠
hypothetical protein - conserved
— OG7
LINF_130006900 ⚠
Lipase (class 3) - putative
— OG7
LINF_340027000 ⚠
hypothetical protein - conserved
— OG7
LINF_200016300 ⚠
phosphatidylinositol 3-kinase - putative
— OG7
LINF_210011700 ⚠
RNA helicase - putative
— OG7
LINF_200020200 ⚠
zinc-binding phosphatase - putative
— OG7
LINF_360073800 ⚠
target of rapamycin (TOR) kinase 1 - putative
— OG7
LINF_350040100 ⚠
acyl transferase-like protein - putative
— OG7
LINF_360066800 ⚠
hypothetical protein - conserved
— OG7
LINF_280006100 ⚠
DNA-direcetd RNA polymerase II - subunit 9 -
— OG7
LINF_310020800 ⚠
hypothetical protein - conserved
— OG7
LINF_190009100 ⚠
DNA-directed RNA polymerase III subunit C11 -
— OG7
LINF_300040000 ⚠
protein mkt1 - putative
— OG7
LINF_120008300 ⚠
Myotubularin-related protein - putative
— OG7
LINF_340048700 ⚠
GRIP domain containing protein - putative
— OG7
LINF_350056400 ⚠
hypothetical protein - conserved
— OG7
LINF_340051500 ⚠
phosphatidylinositol 3-kinase (tor2) - putati
— OG7
LINF_330028200 ⚠
hypothetical protein - conserved
— OG7
LINF_060008900 ⚠
hypothetical protein - conserved
— OG7
LINF_160019300 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LINF_310034200 ⚠
RNA polymerase ii largest subunit
— OG7
LINF_340008700 ⚠
DNA-directed RNA polymerase III subunit C1 -
— OG7
LINF_080010700 ⚠
eukaryotic translation initiation factor 2 be
— OG7
LINF_070009200 ⚠
RAVE protein 1 C terminal - putative
— Both
LINF_160021600 ⚠
WD domain - G-beta repeat - putative
— Both
LINF_220022200 ⚠
hypothetical protein - conserved
— Both
LINF_350008000 ⚠
hypothetical protein - conserved
— Both
LINF_150013800 ⚠
Kelch motif/Galactose oxidase - central domai
— Both
LINF_200018800 ⚠
RNasePH-like protein
— Both
LINF_210014100 ⚠
Temperature dependent protein affecting M2 ds
— Both
LINF_360061900 ⚠
glycosyl hydrolase - putative
— Both
LINF_300016700
RNA-binding protein - putative
— OG6
LINF_260011000 ⚠
hypothetical protein - conserved
— Both
LINF_360050600 ⚠
DNA-directed RNA polymerase I subunit - putat
— Both
LINF_310018600 ⚠
Protein of unknown function (DUF3638)/Protein
— Both
LINF_040006300 ⚠
exosome complex exonuclease RRP40 - putative
— Both
LINF_030008300 ⚠
protein kinase - putative
— Both
LINF_180017900 ⚠
pre-RNA processing PIH1/Nop17 - putative
— OG7
LINF_350049100 ⚠
pre-RNA processing PIH1/Nop17 - putative
— OG7
LINF_270028900 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_340047100 ⚠
target of rapamycin kinase 3
— OG7
LINF_320020300 ⚠
phosphatidylinositol 3-related kinase - putat
— OG7
LINF_040013900 ⚠
hypothetical protein - conserved
— OG7
LINF_360037400 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LINF_080009300 ⚠
hypothetical protein - conserved
— OG7
LINF_350027800 ⚠
hypothetical protein - conserved
— OG7
LINF_320035600 ⚠
CS domain/TPR repeat/Tetratricopeptide repeat
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.