LINF_310034500

2-oxoglutarate dehydrogenase - e3 component - lipoamidedehydrogenase-like protein
Leishmania infantum JPCM5 OG6: OG6_158283 OG7: OG7_0001633 113 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 113 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_250011500 ⚠
RNA polymerase I second largest subunit - put
— Both
LINF_200005000 ⚠
DNA-directed RNA polymerase II subunit 2 - pu
— OG7
LINF_310006600 ⚠
DNA-directed RNA polymerase II subunit 2 - pu
— OG7
LINF_320020300 ⚠
phosphatidylinositol 3-related kinase - putat
— OG7
LINF_290025700 ⚠
dihydrolipoamide dehydrogenase - putative
— +1 more Both
LINF_360037400 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LINF_200016300 ⚠
phosphatidylinositol 3-kinase - putative
— OG7
LINF_360073800 ⚠
target of rapamycin (TOR) kinase 1 - putative
— OG7
LINF_020006200 ⚠
phosphatidylinositol kinase related protein -
— OG7
LINF_340051500 ⚠
phosphatidylinositol 3-kinase (tor2) - putati
— OG7
LINF_340047100 ⚠
target of rapamycin kinase 3
— +1 more Both
LINF_310034600 ⚠
acetoin dehydrogenase e3 component-like prote
— +2 more Both
LINF_160008900 ⚠
tubulin tyrosine ligase - putative
— Both
LINF_240027200 ⚠
hypothetical protein - conserved
— Both
LINF_310018600 ⚠
Protein of unknown function (DUF3638)/Protein
— Both
LINF_230006200 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LINF_280026300 ⚠
hypothetical protein - conserved
— Both
LINF_170016400 ⚠
formin - putative
— OG7
LINF_280034800 ⚠
receptor for activated C kinase 1
— OG7
LINF_300019600 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_280034700 ⚠
receptor for activated C kinase 1
— OG7
LINF_360011300 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_350049100 ⚠
pre-RNA processing PIH1/Nop17 - putative
— OG7
LINF_240014300 ⚠
DNA replication licensing factor MCM5 - putat
— OG7
LINF_320036900 ⚠
DNA replication licensing factor MCM7 - putat
— OG7
LINF_050008300 ⚠
DNA replication licensing factor MCM8 - putat
— OG7
LINF_090008100 ⚠
DNA replication licensing factor MCM4 - puta
— OG7
LINF_330036300 ⚠
DNA replication licensing factor MCM3 - putat
— OG7
LINF_280030800 ⚠
DNA replication licensing factor MCM6 - putat
— OG7
LINF_350054700 ⚠
DNA replication licensing factor MCM9 - putat
— OG7
LINF_290007600 ⚠
Tubulin-tyrosine ligase family - putative
— OG7
LINF_320036500 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_330037100 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LINF_310026800 ⚠
ubiquitin-fusion protein
— OG7
LINF_090015200 ⚠
Ubiquitin-2 like Rad60 SUMO-like/Ubiquitin fa
— OG7
LINF_110015900 ⚠
adaptin-related protein-like protein
— OG7
LINF_360079500 ⚠
adaptin complex 1 subunit - putative
— OG7
LINF_140019100 ⚠
ubiquitin/ribosomal protein S27a - putative
— OG7
LINF_310028300 ⚠
ubiquitin-fusion protein
— OG7
LINF_360011600 ⚠
ubiquitin/ribosomal protein S27a - putative
— OG7
LINF_360043900 ⚠
polyubiquitin - putative
— OG7
LINF_160011200 ⚠
carbamoyl-phosphate synthase - putative
— OG7
LINF_350005600 ⚠
2-oxoisovalerate dehydrogenase beta subunit -
— OG7
LINF_360023600 ⚠
neurobeachin/beige protein - putative
— OG7
LINF_340008700 ⚠
DNA-directed RNA polymerase III subunit C1 -
— OG7
LINF_310034200 ⚠
RNA polymerase ii largest subunit
— OG7
LINF_200012800 ⚠
tubulin-tyrosine ligase - putative
— OG7
LINF_270033100 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_110008900 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LINF_190022000 ⚠
inosine-5'-monophosphate dehydrogenase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.