LINF_350005600

2-oxoisovalerate dehydrogenase beta subunit - mitochondrial precursor - putative
Leishmania infantum JPCM5 OG6: OG6_101601 OG7: OG7_0003147 25 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 25 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_210022900
2-oxoisovalerate dehydrogenase alpha subunit
— Both
LINF_290030100 ⚠
metallo-peptidase - Clan MA(E) Family M1
— OG7
LINF_360042200 ⚠
Bromodomain - putative
— OG7
LINF_120016700 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LINF_360080800 ⚠
DNA-binding protein - putative
— OG7
LINF_310034500 ⚠
2-oxoglutarate dehydrogenase - e3 component -
— OG7
LINF_360039100
ATP synthase - putative
— Both
LINF_160011200
carbamoyl-phosphate synthase - putative
— Both
LINF_050006700
dihydrolipoamide branched chain transacylase
— Both
LINF_290025700 ⚠
dihydrolipoamide dehydrogenase - putative
— Both
LINF_110011600
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
LINF_310040300 ⚠
methylcrotonoyl-coa carboxylase biotinylated
— Both
LINF_310034600 ⚠
acetoin dehydrogenase e3 component-like prote
— Both
LINF_330034600 ⚠
carboxypeptidase - putative
— Both
LINF_010005400 ⚠
carboxylase - putative
— OG6
LINF_170014800 ⚠
guanosine monophosphate reductase
— OG6
LINF_190022000 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
LINF_030006800
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
LINF_060014300
dihydrofolate reductase-thymidylate synthase
— Both
LINF_260008000 ⚠
aminopeptidase-like protein
— Both
LINF_360037800 ⚠
bromodomain factor 2 protein - putative
— Both
LINF_360072600 ⚠
carboxypeptidase - putative
— Both
LINF_140006700 ⚠
carboxypeptidase - putative
— Both
LINF_130005800 ⚠
carboxypeptidase - putative
— Both
LINF_360030700
tyrosine aminotransferase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.