LINF_190022000

inosine-5'-monophosphate dehydrogenase
Leishmania infantum JPCM5 OG6: OG6_100534 OG7: OG7_0002926 86 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 86 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_160019800 ⚠
EMG1/NEP1 methyltransferase - putative
— OG6
LINF_260030600 ⚠
hypothetical protein
— OG7
LINF_300009700 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_100007000 ⚠
MORN repeat - putative
— OG7
LINF_320013000 ⚠
RNA binding protein - putative
— OG6
LINF_270014500 ⚠
hypothetical protein - conserved
— OG6
LINF_180015800 ⚠
5-oxoprolinase - putative
— Both
LINF_030014100 ⚠
peter pan protein - putative
— OG6
LINF_020008100 ⚠
Soluble NSF attachment protein - SNAP - putat
— Both
LINF_080009200 ⚠
WD domain - G-beta repeat - putative
— Both
LINF_110014600 ⚠
Leucine Rich repeat - putative
— Both
LINF_310008400 ⚠
CRAL/TRIO domain containing protein - putativ
— OG7
LINF_350005600 ⚠
2-oxoisovalerate dehydrogenase beta subunit -
— Both
LINF_160011200 ⚠
carbamoyl-phosphate synthase - putative
— Both
LINF_300011300 ⚠
ribosome biogenesis regulatory protein (RRS1)
— OG6
LINF_300035100 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— Both
LINF_290025700 ⚠
dihydrolipoamide dehydrogenase - putative
— Both
LINF_250017900 ⚠
ATP synthase subunit beta - mitochondrial - p
— Both
LINF_110011600 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
LINF_350015500 ⚠
KRI1-like family/KRI1-like family C-terminal
— OG6
LINF_300035200 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— Both
LINF_260005100 ⚠
brix domain containing-like protein
— OG6
LINF_060013800
hypothetical protein - conserved
— OG7
LINF_330030600
hypothetical protein - conserved
— OG7
LINF_360038000 ⚠
ATP-dependent RNA helicase - putative
— OG7
LINF_260019200 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LINF_350048400 ⚠
predicted zinc finger protein
— OG7
LINF_140018100 ⚠
ras-like small GTPases - putative
— OG7
LINF_260017600 ⚠
hypothetical protein - conserved
— OG7
LINF_190015000 ⚠
FYVE zinc finger containing protein - putativ
— OG7
LINF_350040400 ⚠
zinc finger protein - putative
— OG7
LINF_350053100 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— OG7
LINF_310034500 ⚠
2-oxoglutarate dehydrogenase - e3 component -
— OG7
LINF_350017600 ⚠
hypothetical protein - conserved
— OG6
LINF_090019100 ⚠
hypothetical protein - conserved
— OG7
LINF_090019000 ⚠
hypothetical protein - conserved
— OG7
LINF_330034900 ⚠
metallo-peptidase - Clan MF - Family M17
— OG7
LINF_210016300 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_260030700 ⚠
hypothetical protein
— OG7
LINF_310008900 ⚠
CRAL/TRIO domain containing protein - putativ
— OG7
LINF_330039400 ⚠
hypothetical protein - conserved
— OG7
LINF_340048100 ⚠
geranylgeranyltransferase - putative
— OG7
LINF_290011000 ⚠
NF-X1 type zinc finger containing protein - p
— OG7
LINF_350022200 ⚠
casein kinase II - putative
— OG6
LINF_260013300 ⚠
hypothetical protein - conserved
— Both
LINF_330039200 ⚠
hypothetical protein - conserved
— Both
LINF_230010200 ⚠
SNF1-related protein kinase regulatory subuni
— Both
LINF_220005600 ⚠
transcription factor-like protein
— Both
LINF_280025500 ⚠
p21-C-terminal region-binding protein - putat
— Both
LINF_290023700 ⚠
MORN repeat - putative
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.