LINF_170014800

guanosine monophosphate reductase
Leishmania infantum JPCM5 OG6: OG6_100534 OG7: OG7_0002928 63 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 63 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_110011600 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— OG6
LINF_250018800 ⚠
hypothetical protein - conserved
— OG6
LINF_070011000 ⚠
hypothetical protein - conserved
— OG6
LINF_180017700 ⚠
prolyl-tRNA synthetase - putative
— OG6
LINF_180017600 ⚠
prolyl-tRNA synthetase - putative
— OG6
LINF_320035500 ⚠
Prefoldin subunit - putative
— OG6
LINF_270017000 ⚠
cysteine desulfurase - putative
— Both
LINF_110014900 ⚠
PUB domain containing protein - putative
— OG6
LINF_360030600 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
LINF_300035000 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— OG6
LINF_250018000 ⚠
ATP synthase subunit beta - mitochondrial - p
— OG6
LINF_310034600 ⚠
acetoin dehydrogenase e3 component-like prote
— OG6
LINF_350017600 ⚠
hypothetical protein - conserved
— Both
LINF_260005100 ⚠
brix domain containing-like protein
— Both
LINF_300035200 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— OG6
LINF_350015500 ⚠
KRI1-like family/KRI1-like family C-terminal
— Both
LINF_030011900 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG6
LINF_250017900 ⚠
ATP synthase subunit beta - mitochondrial - p
— OG6
LINF_290025700 ⚠
dihydrolipoamide dehydrogenase - putative
— OG6
LINF_300035100 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— OG6
LINF_300011300 ⚠
ribosome biogenesis regulatory protein (RRS1)
— Both
LINF_160011200 ⚠
carbamoyl-phosphate synthase - putative
— OG6
LINF_350005600 ⚠
2-oxoisovalerate dehydrogenase beta subunit -
— OG6
LINF_160019800 ⚠
EMG1/NEP1 methyltransferase - putative
— Both
LINF_110014600 ⚠
Leucine Rich repeat - putative
— OG6
LINF_080009200 ⚠
WD domain - G-beta repeat - putative
— OG6
LINF_020008100 ⚠
Soluble NSF attachment protein - SNAP - putat
— OG6
LINF_030014100 ⚠
peter pan protein - putative
— Both
LINF_180015800 ⚠
5-oxoprolinase - putative
— OG6
LINF_270014500 ⚠
hypothetical protein - conserved
— Both
LINF_320013000 ⚠
RNA binding protein - putative
— Both
LINF_270029800 ⚠
EMG1/NEP1 methyltransferase - putative
— OG7
LINF_290023700 ⚠
MORN repeat - putative
— OG6
LINF_110012000 ⚠
aminopeptidase - putative
— OG6
LINF_270014700 ⚠
hypothetical protein - conserved
— Both
LINF_200021200 ⚠
ribosome biogenesis protein - putative
— Both
LINF_020011900 ⚠
Nop14-like family - putative
— OG6
LINF_250018300 ⚠
hypothetical protein - conserved
— Both
LINF_310022000 ⚠
Leucine Rich repeat - putative
— OG6
LINF_210015700 ⚠
Domain of unknown function (DUF4042)/HEAT-lik
— OG6
LINF_330036700 ⚠
translation initiation factor IF-2 - putative
— OG6
LINF_300010700 ⚠
hypothetical protein - conserved
— OG6
LINF_310008300 ⚠
CRAL/TRIO domain containing protein - putativ
— OG6
LINF_350022200 ⚠
casein kinase II - putative
— OG6
LINF_290031300 ⚠
aspartyl aminopeptidase - putative
— OG6
LINF_350033000 ⚠
hypothetical protein - conserved
— OG6
LINF_310029900 ⚠
ARM-like helical domain-containing protein
— OG6
LINF_360019900 ⚠
hypothetical protein - conserved
— OG6
LINF_110011900 ⚠
aminopeptidase - putative
— OG6
LINF_280025500 ⚠
p21-C-terminal region-binding protein - putat
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.