LINF_170016300

ATP-dependent RNA helicase - putative
Leishmania infantum JPCM5 OG6: OG6_100305 OG7: OG7_0001850 139 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 139 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_160018000 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LINF_280027800 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LINF_360038700 ⚠
cullin-like protein
— OG7
LINF_360031500 ⚠
Cullin protein neddylation domain containing
— OG7
LINF_310038500 ⚠
acetyl-CoA carboxylase - putative
— Both
LINF_240029100 ⚠
cullin-like protein-like protein
— OG7
LINF_250018900 ⚠
Cullin family/Cullin protein neddylation doma
— Both
LINF_260019200 ⚠
MORN repeat/FYVE zinc finger containing prote
— Both
LINF_340048700 ⚠
GRIP domain containing protein - putative
— Both
LINF_310019900 ⚠
Protein phosphatase 2C - putative
— OG6
LINF_180013400 ⚠
hypothetical protein - conserved
— Both
LINF_310018600 ⚠
Protein of unknown function (DUF3638)/Protein
— Both
LINF_340034000 ⚠
hypothetical protein - conserved
— Both
LINF_240015800 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— Both
LINF_130015900 ⚠
proteasome regulatory ATPase subunit 2 - puta
— OG6
LINF_080005000 ⚠
adaptor complex protein (AP) 3 delta subunit
— Both
LINF_150019300 ⚠
Cyclic nucleotide-binding domain containing p
— Both
LINF_020008700 ⚠
proteasome regulatory non-ATPase subunit 6 -
— Both
LINF_270021500 ⚠
proteasome regulatory non-ATP-ase subunit 3 -
— Both
LINF_080010200 ⚠
ribose-phosphate pyrophosphokinase - putative
— Both
LINF_320028300 ⚠
U5 small nuclear ribonucleoprotein component
— Both
LINF_320046500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LINF_360052900 ⚠
19S proteasome regulatory subunit
— OG6
LINF_330008000 ⚠
WD domain - G-beta repeat - putative
— Both
LINF_320027400 ⚠
RNA recognition motif. (a.k.a. RRM - RBD - or
— Both
LINF_080016200 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LINF_330028000 ⚠
phosphoribosylpyrophosphate synthetase - puta
— OG7
LINF_360063600 ⚠
phosphoribosylpyrophosphate synthetase - puta
— OG7
LINF_210021500 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LINF_160005200 ⚠
Holliday junction DNA helicase ruvB N-terminu
— OG7
LINF_340047100 ⚠
target of rapamycin kinase 3
— OG7
LINF_320020300 ⚠
phosphatidylinositol 3-related kinase - putat
— OG7
LINF_310034200 ⚠
RNA polymerase ii largest subunit
— OG7
LINF_260017600 ⚠
hypothetical protein - conserved
— OG7
LINF_230026400 ⚠
neutral sphingomyelinase activation associate
— OG7
LINF_140018100 ⚠
ras-like small GTPases - putative
— OG7
LINF_070008000 ⚠
ubiquitin-protein ligase-like - putative
— OG7
LINF_330037100 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LINF_270019200 ⚠
ubiquitin carboxyl-terminal hydrolase - putat
— OG7
LINF_310006600 ⚠
DNA-directed RNA polymerase II subunit 2 - pu
— OG7
LINF_340051500 ⚠
phosphatidylinositol 3-kinase (tor2) - putati
— OG7
LINF_340008700 ⚠
DNA-directed RNA polymerase III subunit C1 -
— OG7
LINF_040014600 ⚠
adenylate kinase - putative
— OG7
LINF_160017100 ⚠
WW domain containing protein - putative
— OG7
LINF_340052400 ⚠
hypothetical protein - conserved
— OG7
LINF_320036300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_350029400 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_330008900 ⚠
ATP-binding cassette sub-family F member 1 -
— OG7
LINF_360007000 ⚠
elongation factor 2
— OG7
LINF_250027700 ⚠
elongation factor 2-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.