LINF_240015800

AKAP7 2'5' RNA ligase-like domain containing protein - putative
Leishmania infantum JPCM5 OG6: OG6_163296 OG7: OG7_0051916 93 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 93 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_200020200 ⚠
zinc-binding phosphatase - putative
— OG7
LINF_350029400 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_320036300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_040014600 ⚠
adenylate kinase - putative
— OG7
LINF_360019700 ⚠
adenylate kinase - putative
— OG7
LINF_320019300 ⚠
RNA guanylyltransferase - putative
— OG7
LINF_160005200 ⚠
Holliday junction DNA helicase ruvB N-terminu
— OG7
LINF_290006300 ⚠
RNA polymerase subunit - putative
— OG7
LINF_230023100 ⚠
DNA polymerase theta (helicase domain only) -
— OG7
LINF_320019700 ⚠
ATP-dependent DNA DEAD/DEAH box helicase - pu
— OG7
LINF_330023700 ⚠
elongation factor 1-gamma - putative
— OG7
LINF_120008700 ⚠
Glutathione S-transferase - N-terminal domain
— OG7
LINF_270019200 ⚠
ubiquitin carboxyl-terminal hydrolase - putat
— OG7
LINF_360063600 ⚠
phosphoribosylpyrophosphate synthetase - puta
— OG7
LINF_330028000 ⚠
phosphoribosylpyrophosphate synthetase - puta
— OG7
LINF_080016200 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LINF_080010200 ⚠
ribose-phosphate pyrophosphokinase - putative
— Both
LINF_070006500
Eukaryotic membrane protein family - putative
— Both
LINF_140020800
hypothetical protein - conserved
— Both
LINF_180013400
hypothetical protein - conserved
— Both
LINF_340034000
hypothetical protein - conserved
— Both
LINF_260019200 ⚠
MORN repeat/FYVE zinc finger containing prote
— Both
LINF_260029200
Zn-finger in Ran binding protein and others/S
— Both
LINF_340048700
GRIP domain containing protein - putative
— Both
LINF_140017600 ⚠
hypothetical protein - conserved
— OG7
LINF_190012900 ⚠
ABC transport system ATP-binding protein - pu
— OG7
LINF_330008900 ⚠
ATP-binding cassette sub-family F member 1 -
— OG7
LINF_350049100 ⚠
pre-RNA processing PIH1/Nop17 - putative
— OG7
LINF_210021500 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LINF_050009000 ⚠
structural maintenance of chromosome (SMC) -
— OG7
LINF_350040500 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LINF_160017100 ⚠
WW domain containing protein - putative
— OG7
LINF_320045900 ⚠
Unconventional myosin
— OG7
LINF_340031100 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LINF_180011100 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LINF_350048400 ⚠
predicted zinc finger protein
— OG7
LINF_340014500
hypothetical protein - conserved
— Both
LINF_240007500 ⚠
Dynein intermediate chain 1 - axonemal
— OG7
LINF_300014700 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_190015000 ⚠
FYVE zinc finger containing protein - putativ
— OG7
LINF_350040400 ⚠
zinc finger protein - putative
— OG7
LINF_070008000 ⚠
ubiquitin-protein ligase-like - putative
— OG7
LINF_290005900 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_070006200 ⚠
Sec7 domain containing protein - putative
— OG7
LINF_140018100 ⚠
ras-like small GTPases - putative
— OG7
LINF_260017600 ⚠
hypothetical protein - conserved
— OG7
LINF_120008300 ⚠
Myotubularin-related protein - putative
— Both
LINF_130009900 ⚠
ATP-dependent RNA helicase - putative
— Both
LINF_120007000 ⚠
ubiquitin hydrolase - putative
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.