LINF_080016200

phosphoribosylpyrophosphate synthetase
Leishmania infantum JPCM5 OG6: OG6_143547 OG7: OG7_0002319 168 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 168 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_310038500 ⚠
acetyl-CoA carboxylase - putative
— +5 more Both
LINF_080010200 ⚠
ribose-phosphate pyrophosphokinase - putative
— +4 more Both
LINF_330028000 ⚠
phosphoribosylpyrophosphate synthetase - puta
— +6 more Both
LINF_360063600 ⚠
phosphoribosylpyrophosphate synthetase - puta
— +6 more Both
LINF_310034200 ⚠
RNA polymerase ii largest subunit
— Both
LINF_340008700 ⚠
DNA-directed RNA polymerase III subunit C1 -
— Both
LINF_160019300 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LINF_160018000 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LINF_350040400 ⚠
zinc finger protein - putative
— OG7
LINF_290026600 ⚠
hypothetical protein - conserved
— OG7
LINF_360029500 ⚠
Spc97 / Spc98 family - putative
— OG7
LINF_300016500 ⚠
WW domain containing protein - putative
— OG7
LINF_110015900 ⚠
adaptin-related protein-like protein
— OG7
LINF_200005000 ⚠
DNA-directed RNA polymerase II subunit 2 - pu
— OG7
LINF_120007000 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_100014700 ⚠
hypothetical protein - conserved
— OG7
LINF_190015000 ⚠
FYVE zinc finger containing protein - putativ
— OG7
LINF_250018900 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LINF_140011200 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_320036300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_200016300 ⚠
phosphatidylinositol 3-kinase - putative
— OG7
LINF_190011500 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
LINF_210028600 ⚠
histone deacetylase - putative
— OG7
LINF_180013500 ⚠
Periodic tryptophan protein 2 homolog - putat
— OG7
LINF_150014400 ⚠
hypothetical protein - conserved
— OG7
LINF_360073800 ⚠
target of rapamycin (TOR) kinase 1 - putative
— OG7
LINF_360031500 ⚠
Cullin protein neddylation domain containing
— OG7
LINF_330029600 ⚠
mitogen-activated protein kinase - putative
— OG7
LINF_360066800 ⚠
hypothetical protein - conserved
— OG7
LINF_360038700 ⚠
cullin-like protein
— OG7
LINF_300018400 ⚠
hypothetical protein - conserved
— OG7
LINF_340020700 ⚠
hypothetical protein - conserved
— OG7
LINF_300014700 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_300029800 ⚠
hypothetical protein - conserved
— OG7
LINF_300042900 ⚠
CPSF-domain protein - putative
— OG7
LINF_050014100 ⚠
CPSF A subunit region containing protein - pu
— OG7
LINF_020006200 ⚠
phosphatidylinositol kinase related protein -
— OG7
LINF_100006200 ⚠
hypothetical protein - conserved
— OG7
LINF_290006300 ⚠
RNA polymerase subunit - putative
— OG7
LINF_340048700 ⚠
GRIP domain containing protein - putative
— OG7
LINF_350048400 ⚠
predicted zinc finger protein
— OG7
LINF_180011100 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LINF_360023600 ⚠
neurobeachin/beige protein - putative
— OG7
LINF_310006600 ⚠
DNA-directed RNA polymerase II subunit 2 - pu
— OG7
LINF_350029400 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_280027800 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LINF_210021500 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LINF_350040500 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LINF_050009000 ⚠
structural maintenance of chromosome (SMC) -
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.