LINF_320046500

SPRY domain/HECT-domain (ubiquitin-transferase) - putative
Leishmania infantum JPCM5 OG6: OG6_147203 OG7: OG7_0031172 89 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 89 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_210013400
proteasome regulatory non-ATP-ase subunit 5 -
— Both
LINF_340021000 ⚠
N-terminal region of Chorein - a TM vesicle-m
— OG7
LINF_090016200 ⚠
N-terminal region of Chorein- a TM vesicle-m
— OG7
LINF_160021600 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_300024800
cyclosome subunit-like protein
— Both
LINF_320027400
RNA recognition motif. (a.k.a. RRM - RBD - or
— Both
LINF_090019500
AAA family ATPase - putative
— Both
LINF_360052900
19S proteasome regulatory subunit
— OG6
LINF_320035300
proteasome regulatory non-ATP-ase subunit - p
— Both
LINF_270021500
proteasome regulatory non-ATP-ase subunit 3 -
— Both
LINF_290006100
proteasome regulatory non-ATPase subunit - pu
— Both
LINF_150019300 ⚠
Cyclic nucleotide-binding domain containing p
— Both
LINF_360049700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_170016300 ⚠
ATP-dependent RNA helicase - putative
— Both
LINF_330008000
WD domain - G-beta repeat - putative
— Both
LINF_130009900 ⚠
ATP-dependent RNA helicase - putative
— Both
LINF_170015000
OSM3-like kinesin - putative
— OG6
LINF_120007200
proteasome regulatory ATPase subunittcc1l8.3
— OG6
LINF_190016600
proteasome regulatory non-ATP-ase subunit 9 -
— Both
LINF_320009000
19S proteasome non-atpase subunit 8
— Both
LINF_070018000
proteasome regulatory non-ATP-ase subunit - p
— Both
LINF_240014500
hypothetical protein - conserved
— Both
LINF_120011300 ⚠
Tetratricopeptide repeat/TPR repeat - putativ
— Both
LINF_040010200 ⚠
palmitoyl acyltransferase 1 - putative
— OG7
LINF_130006500 ⚠
protein kinase A regulatory subunit
— OG7
LINF_320046900 ⚠
cAMP response protein 1 - putative
— OG7
LINF_340035100 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LINF_230023100 ⚠
DNA polymerase theta (helicase domain only) -
— OG7
LINF_320019700 ⚠
ATP-dependent DNA DEAD/DEAH box helicase - pu
— OG7
LINF_340052400 ⚠
hypothetical protein - conserved
— OG7
LINF_030007500 ⚠
Apolipoprotein A1/A4/E domain containing prot
— OG7
LINF_200017500 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LINF_340041200 ⚠
cleavage and polyadenylation specificity fact
— OG7
LINF_350031900 ⚠
ankyrin repeat protein - putative
— OG7
LINF_300027500
endosomal trafficking protein RME-8 - putativ
— Both
LINF_340050600 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LINF_330006500 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeat - p
— OG7
LINF_300038300 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LINF_030009600 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LINF_290016900 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LINF_260012500 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_340025200 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_110009100 ⚠
chromatin binding protein - putative
— OG7
LINF_360033800 ⚠
cyclin-e binding protein 1-like protein
— OG7
LINF_310035800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_240025900
hypothetical protein - conserved
— Both
LINF_040010500
Tetratricopeptide repeat/TPR repeat - putativ
— Both
LINF_140013900
kinesin - putative
— OG6
LINF_340012100
proteasome regulatory non-ATPase subunit 11 -
— Both
LINF_220011600
proteasome regulatory ATPase subunit 5 - puta
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.