LINF_340041200

cleavage and polyadenylation specificity factor - putative
Leishmania infantum JPCM5 OG6: OG6_101260 OG7: OG7_0002417 138 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 138 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_250006800 ⚠
cleavage and polyadenylation specificity fact
— Both
LINF_160021600 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_300016800 ⚠
importin alpha - putative
— OG7
LINF_300011400 ⚠
histidyl-tRNA synthetase - putative
— OG7
LINF_220008000 ⚠
hypothetical protein - conserved
— OG7
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— OG7
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— OG7
LINF_300009700 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_340028800 ⚠
asparaginyl-tRNA synthetase - putative
— OG7
LINF_210016300 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_310038600 ⚠
Component of IIS longevity pathway SMK-1 - pu
— OG7
LINF_290016900 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LINF_030009600 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LINF_300038300 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LINF_330006500 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeat - p
— OG7
LINF_340050600 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LINF_040010200 ⚠
palmitoyl acyltransferase 1 - putative
— OG7
LINF_350031900 ⚠
ankyrin repeat protein - putative
— OG7
LINF_180016400 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LINF_110015500 ⚠
hypothetical protein - conserved
— OG7
LINF_290027300 ⚠
hypothetical protein - conserved
— OG7
LINF_300040100 ⚠
DNA ligase I - putative
— OG7
LINF_310040100 ⚠
hypothetical protein - conserved
— OG7
LINF_300010000 ⚠
hypothetical protein - conserved
— OG7
LINF_300027500 ⚠
endosomal trafficking protein RME-8 - putativ
— OG7
LINF_290030200 ⚠
hypothetical protein - conserved
— OG7
LINF_270028900 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_280023900 ⚠
protein kinase - putative
— OG7
LINF_320008200 ⚠
intraflagellar transport protein 140 - putati
— OG7
LINF_360020600 ⚠
N-terminal region of Chorein - a TM vesicle-m
— OG7
LINF_320046500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_200017500 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LINF_250011400 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LINF_300005500 ⚠
MATH domain containing protein - putative
— OG7
LINF_360034100 ⚠
protein kinase - putative
— OG7
LINF_320046900 ⚠
cAMP response protein 1 - putative
— OG7
LINF_240014500 ⚠
hypothetical protein - conserved
— OG7
LINF_200007600 ⚠
Midasin - putative
— OG7
LINF_350008600 ⚠
hypothetical protein - conserved
— OG7
LINF_050013400 ⚠
hypothetical protein - conserved
— OG7
LINF_290022500 ⚠
XPC-binding domain/UBA/TS-N domain containing
— OG7
LINF_060015200 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG7
LINF_040010500 ⚠
Tetratricopeptide repeat/TPR repeat - putativ
— OG7
LINF_340035100 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LINF_240018700 ⚠
translation initiation factor IF-2 - putative
— OG7
LINF_150005300 ⚠
Possible lysine decarboxylase - putative
— OG7
LINF_340045100 ⚠
hypothetical protein - conserved
— OG7
LINF_130016000 ⚠
leucyl-tRNA synthetase - putative
— OG7
LINF_240025900 ⚠
hypothetical protein - conserved
— OG7
LINF_150019400 ⚠
protein kinase - putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.