LINF_250006800

cleavage and polyadenylation specificity factor - putative
Leishmania infantum JPCM5 OG6: OG6_103283 OG7: OG7_0002417 149 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 149 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_340041200 ⚠
cleavage and polyadenylation specificity fact
— Both
LINF_360010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LINF_140020100 ⚠
tyrosyl-tRNA synthetase - putative
— Both
LINF_350051300 ⚠
hypothetical protein - conserved
— Both
LINF_280030600 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LINF_250031400 ⚠
hypothetical protein - conserved
— Both
LINF_270008900 ⚠
Nuclear pore complex protein 158
— Both
LINF_360006300 ⚠
PUB domain containing protein - putative
— Both
LINF_200016600 ⚠
Pre-mRNA-splicing factor 38 - putative
— Both
LINF_350032600 ⚠
acyl-CoA dehydrogenase - putative
— Both
LINF_140020000 ⚠
inositol-3-phosphate synthase
— Both
LINF_210013900 ⚠
methionyl-tRNA synthetase
— Both
LINF_250014500 ⚠
protein kinase - putative
— Both
LINF_360031600 ⚠
dipeptidyl-peptidase 8-like serine peptidase
— Both
LINF_230006100 ⚠
GDP-mannose pyrophosphorylase
— Both
LINF_290005500 ⚠
tryptophanyl-tRNA synthetase - putative
— Both
LINF_140019600 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LINF_250028200 ⚠
Translation initiation factor eIF3 subunit -
— Both
LINF_200021600 ⚠
tRNA (Uracil-5-)-methyltransferase/Protein-L-
— Both
LINF_180005900 ⚠
alpha glucosidase II subunit - putative
— Both
LINF_170009800 ⚠
Dihydrouridine synthase (Dus) - putative
— Both
LINF_180014100
cyclosporin 16 - putative
— OG6
LINF_190012900 ⚠
ABC transport system ATP-binding protein - pu
— Both
LINF_220021600 ⚠
alanyl-tRNA synthetase - putative
— Both
LINF_050013400 ⚠
hypothetical protein - conserved
— Both
LINF_280007900 ⚠
DIS3-like exonuclease - putative
— Both
LINF_240014500 ⚠
hypothetical protein - conserved
— Both
LINF_360066000 ⚠
isoleucyl-tRNA synthetase - putative
— Both
LINF_320047000 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— Both
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— Both
LINF_090019500 ⚠
AAA family ATPase - putative
— Both
LINF_280009200 ⚠
rrp44p homologue - putative
— OG7
LINF_040008400 ⚠
mitochondrial exoribonuclease DSS-1 - putativ
— OG7
LINF_090016200 ⚠
N-terminal region of Chorein- a TM vesicle-m
— OG7
LINF_340021000 ⚠
N-terminal region of Chorein - a TM vesicle-m
— OG7
LINF_210005600 ⚠
BAR domain containing protein - putative
— OG7
LINF_030006400 ⚠
ATP-binding cassette protein subfamily F - me
— OG7
LINF_200017500 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LINF_210016300 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_290016900 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LINF_030009600 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LINF_300038300 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LINF_330006500 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeat - p
— OG7
LINF_340050600 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LINF_040010200 ⚠
palmitoyl acyltransferase 1 - putative
— OG7
LINF_350031900 ⚠
ankyrin repeat protein - putative
— OG7
LINF_290027300 ⚠
hypothetical protein - conserved
— OG7
LINF_130006500 ⚠
protein kinase A regulatory subunit
— OG7
LINF_340035100 ⚠
regulatory subunit of protein kinase a-like p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.