LINF_180014100

cyclosporin 16 - putative
Leishmania infantum JPCM5 OG6: OG6_152675 OG7: OG7_0000556 78 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 78 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_220008000
hypothetical protein - conserved
— OG6
LINF_220018500
translation initiation factor IF-2 - putative
— OG6
LINF_180005000
kinetoplast polyadenylation/uridylation facto
— OG6
LINF_180005900
alpha glucosidase II subunit - putative
— OG6
LINF_300038700
UV excision repair RAD23-like protein
— OG6
LINF_300040100
DNA ligase I - putative
— OG6
LINF_180011900
HEAT repeats/HEAT repeat - putative
— OG6
LINF_300014700
ubiquitin-protein ligase - putative
— OG6
LINF_060015200
glucosamine-fructose-6-phosphate aminotransfe
— OG6
LINF_290022500
XPC-binding domain/UBA/TS-N domain containing
— OG6
LINF_350009100
hypothetical protein - conserved
— OG6
LINF_110014600
Leucine Rich repeat - putative
— OG6
LINF_310034100
calreticulin - putative
— OG6
LINF_130014100
Axonemal dynein light chain - putative
— OG6
LINF_340045100
hypothetical protein - conserved
— OG6
LINF_340028800
asparaginyl-tRNA synthetase - putative
— OG6
LINF_350008600
hypothetical protein - conserved
— OG6
LINF_350032600
acyl-CoA dehydrogenase - putative
— OG6
LINF_130016000
leucyl-tRNA synthetase - putative
— OG6
LINF_110011000
hypothetical protein - conserved
— OG6
LINF_220021600
alanyl-tRNA synthetase - putative
— OG6
LINF_190012900
ABC transport system ATP-binding protein - pu
— OG6
LINF_240011400
Kinesin-13 3 - putative
— OG6
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— OG6
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— OG6
LINF_360036300
Phytochelatin synthase - putative
— OG6
LINF_320047000
Gar1/Naf1 RNA binding region containing prote
— OG6
LINF_360066000
isoleucyl-tRNA synthetase - putative
— OG6
LINF_280007900
DIS3-like exonuclease - putative
— OG6
LINF_050013400
hypothetical protein - conserved
— OG6
LINF_290027900
5'-AMP-activated protein kinase catalytic sub
— OG6
LINF_250006800
cleavage and polyadenylation specificity fact
— OG6
LINF_180011100
Zn-finger in Ran binding protein and others/F
— OG6
LINF_360005700 ⚠
stress-inducible protein STI1 homolog
— OG6
LINF_270032100 ⚠
TPR-repeat protein - putative
— OG6
LINF_360028800 ⚠
NOL1/NOP2/sun family - putative
— OG6
LINF_290033200 ⚠
NOL1/NOP2/sun family/FtsJ-like methyltransfer
— OG6
LINF_290028800
UDP-glucose:Glycoprotein Glucosyltransferase
— OG6
LINF_260017900
Cupin-like domain containing protein - putati
— OG6
LINF_200007500 ⚠
deoxyhypusine synthase - putative
— OG6
LINF_280030600 ⚠
serine hydroxymethyltransferase (SHMT-L)
— OG6
LINF_140020100
tyrosyl-tRNA synthetase - putative
— OG6
LINF_140009900
N-terminal conserved domain of Nudc./CS domai
— OG6
LINF_150014300
hypothetical protein - conserved
— OG6
LINF_200012400
conserved protein - unknown function
— OG6
LINF_300028600
SET domain containing protein - putative
— OG6
LINF_300016800
importin alpha - putative
— OG6
LINF_300036900
valyl-tRNA synthetase - putative
— OG6
LINF_350015200
protein kinase - putative
— OG6
LINF_250031400
hypothetical protein - conserved
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.