LINF_300040100

DNA ligase I - putative
Leishmania infantum JPCM5 OG6: OG6_100906 OG7: OG7_0002598 158 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 158 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_170009800 ⚠
Dihydrouridine synthase (Dus) - putative
— Both
LINF_310027100 ⚠
dihydrouridine synthase (Dus) - putative
— Both
LINF_030012700 ⚠
Ubiquitin-like domain containing protein - pu
— Both
LINF_340018100 ⚠
Dihydrouridine synthase (Dus) - putative
— OG7
LINF_360010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LINF_350054800 ⚠
tubulin tyrosine ligase - putative
— OG7
LINF_350007000 ⚠
NLI interacting factor-like phosphatase - put
— Both
LINF_340045100 ⚠
hypothetical protein - conserved
— Both
LINF_340028800 ⚠
asparaginyl-tRNA synthetase - putative
— Both
LINF_180014100
cyclosporin 16 - putative
— OG6
LINF_170018900 ⚠
UDP-sugar pyrophosphorylase
— Both
LINF_350015200
protein kinase - putative
— OG6
LINF_350009100 ⚠
hypothetical protein - conserved
— Both
LINF_190012900 ⚠
ABC transport system ATP-binding protein - pu
— Both
LINF_300038700 ⚠
UV excision repair RAD23-like protein
— Both
LINF_180005000 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
LINF_300036700 ⚠
S-adenosylmethionine decarboxylase
— Both
LINF_270014800 ⚠
WD domain - G-beta repeat - putative
— Both
LINF_280022100 ⚠
phosphonopyruvate decarboxylase-like protein
— Both
LINF_220018500 ⚠
translation initiation factor IF-2 - putative
— Both
LINF_020008600
casein kinase II - alpha chain - putative
— OG6
LINF_220021600 ⚠
alanyl-tRNA synthetase - putative
— Both
LINF_050013400 ⚠
hypothetical protein - conserved
— Both
LINF_280007900 ⚠
DIS3-like exonuclease - putative
— Both
LINF_210017100 ⚠
Programmed cell death protein 2 - C-terminal
— Both
LINF_280024500 ⚠
replication factor A - 51kDa subunit - putati
— Both
LINF_220017200 ⚠
Metallo-beta-lactamase superfamily/Beta-lacta
— Both
LINF_220017300 ⚠
Metallo-beta-lactamase superfamily/Beta-lacta
— Both
LINF_320047000 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
LINF_030012500 ⚠
TatD related DNase - putative
— Both
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— Both
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— Both
LINF_230025400 ⚠
hypothetical protein - conserved
— Both
LINF_280009200 ⚠
rrp44p homologue - putative
— OG7
LINF_040008400 ⚠
mitochondrial exoribonuclease DSS-1 - putativ
— OG7
LINF_100012500 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LINF_260026100 ⚠
hypothetical protein - conserved
— OG7
LINF_080008000 ⚠
Isochorismatase family - putative
— OG7
LINF_290007600 ⚠
Tubulin-tyrosine ligase family - putative
— OG7
LINF_080008100 ⚠
Isochorismatase family - putative
— OG7
LINF_320036500 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_120005600 ⚠
ribonuclease mar1
— OG7
LINF_250027200 ⚠
NLI interacting factor-like phosphatase - put
— OG7
LINF_210016300 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_290031700 ⚠
NLI interacting factor-like phosphatase - put
— OG7
LINF_350031400 ⚠
TFIIF-stimulated CTD phosphatase - putative
— OG7
LINF_330022300 ⚠
protein kinase - putative
— OG7
LINF_210005500 ⚠
hypothetical protein - conserved
— OG7
LINF_240005900 ⚠
Poly A polymerase regulatory subunit - putati
— OG7
LINF_340041200 ⚠
cleavage and polyadenylation specificity fact
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.