LINF_310027100

dihydrouridine synthase (Dus) - putative
Leishmania infantum JPCM5 OG6: OG6_101867 OG7: OG7_0002064 216 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 216 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_290027300 ⚠
hypothetical protein - conserved
— OG7
LINF_300040100 ⚠
DNA ligase I - putative
— Both
LINF_180008700 ⚠
tubulin tyrosine ligase protein - putative
— OG7
LINF_360031600 ⚠
dipeptidyl-peptidase 8-like serine peptidase
— OG7
LINF_330022300 ⚠
protein kinase - putative
— OG7
LINF_250014500 ⚠
protein kinase - putative
— OG7
LINF_180005900 ⚠
alpha glucosidase II subunit - putative
— OG7
LINF_360050100 ⚠
glycosyl hydrolase-like protein
— OG7
LINF_310038600 ⚠
Component of IIS longevity pathway SMK-1 - pu
— OG7
LINF_210016300 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_340028800 ⚠
asparaginyl-tRNA synthetase - putative
— OG7
LINF_300009700 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— OG7
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— OG7
LINF_220008000 ⚠
hypothetical protein - conserved
— OG7
LINF_300011400 ⚠
histidyl-tRNA synthetase - putative
— OG7
LINF_300016800 ⚠
importin alpha - putative
— OG7
LINF_200021600 ⚠
tRNA (Uracil-5-)-methyltransferase/Protein-L-
— OG7
LINF_300033700 ⚠
GTPase activator-like protein
— OG7
LINF_170022000 ⚠
Rab-GTPase-TBC domain containing protein - pu
— OG7
LINF_360066000 ⚠
isoleucyl-tRNA synthetase - putative
— OG7
LINF_160009000 ⚠
XRN 5'-3' exonuclease N-terminus - putative
— OG7
LINF_180011900 ⚠
HEAT repeats/HEAT repeat - putative
— OG7
LINF_360070700 ⚠
rab-like GTPase activating protein - putative
— OG7
LINF_360070600 ⚠
disgorgin - putative
— OG7
LINF_310034100 ⚠
calreticulin - putative
— OG7
LINF_160008900 ⚠
tubulin tyrosine ligase - putative
— OG7
LINF_270033100 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_260018700 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LINF_360006800 ⚠
elongation factor 2
— OG7
LINF_360007000 ⚠
elongation factor 2
— OG7
LINF_320028300 ⚠
U5 small nuclear ribonucleoprotein component
— OG7
LINF_250028200 ⚠
Translation initiation factor eIF3 subunit -
— OG7
LINF_350032600 ⚠
acyl-CoA dehydrogenase - putative
— OG7
LINF_130014100 ⚠
Axonemal dynein light chain - putative
— OG7
LINF_030006400 ⚠
ATP-binding cassette protein subfamily F - me
— OG7
LINF_110011000 ⚠
hypothetical protein - conserved
— OG7
LINF_330008900 ⚠
ATP-binding cassette sub-family F member 1 -
— OG7
LINF_190012900 ⚠
ABC transport system ATP-binding protein - pu
— OG7
LINF_330033100 ⚠
ras-like small GTPases - putative
— OG7
LINF_350057700 ⚠
GTP-binding protein - putative
— OG7
LINF_050009600 ⚠
GTPase - putative
— OG7
LINF_290007600 ⚠
Tubulin-tyrosine ligase family - putative
— OG7
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_350054800 ⚠
tubulin tyrosine ligase - putative
— OG7
LINF_300028200 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_120005600 ⚠
ribonuclease mar1
— OG7
LINF_320036500 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LINF_080008100 ⚠
Isochorismatase family - putative
— OG7
LINF_350056100 ⚠
hypothetical protein - conserved
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.