LINF_280007900

DIS3-like exonuclease - putative
Leishmania infantum JPCM5 OG6: OG6_102526 OG7: OG7_0002439 241 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 241 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_110012000 ⚠
aminopeptidase - putative
— OG7
LINF_250014500 ⚠
protein kinase - putative
— +1 more Both
LINF_120015400 ⚠
N-acyl-L-amino acid amidohydrolase
— Both
LINF_200022100 ⚠
amidohydrolase - putative
— Both
LINF_310017700 ⚠
amidohydrolase - putative
— Both
LINF_300019400 ⚠
amidohydrolase - putative
— Both
LINF_110011900 ⚠
aminopeptidase - putative
— OG7
LINF_140020000 ⚠
inositol-3-phosphate synthase
— +1 more Both
LINF_150014300 ⚠
hypothetical protein - conserved
— Both
LINF_200022000 ⚠
amidohydrolase - putative
— Both
LINF_330022300 ⚠
protein kinase - putative
— OG7
LINF_310017600 ⚠
amidohydrolase - putative
— OG7
LINF_330034900 ⚠
metallo-peptidase - Clan MF - Family M17
— +1 more Both
LINF_350051300 ⚠
hypothetical protein - conserved
— +1 more Both
LINF_200022200 ⚠
amidohydrolase - putative
— Both
LINF_250024000 ⚠
hypothetical protein - conserved
— OG7
LINF_340021900 ⚠
EAP30/Vps36 family - putative
— OG7
LINF_100015600 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LINF_300020500 ⚠
phosphopantothenoylcysteine decarboxylase - p
— OG7
LINF_190014900 ⚠
peptidyl-prolyl cis-trans isomerase - macroph
— OG7
LINF_310020900 ⚠
hypothetical protein - conserved
— OG7
LINF_190021700 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LINF_300036300 ⚠
tRNA (Guanine-1)-methyltransferase - putative
— OG7
LINF_290018300 ⚠
Hsp70 protein/TPR repeat/Tetratricopeptide re
— OG7
LINF_360007500 ⚠
peptidyl-prolyl cis-trans isomerase - putativ
— OG7
LINF_290028300 ⚠
hypothetical protein - conserved
— OG7
LINF_130011300 ⚠
hypothetical protein - conserved
— OG7
LINF_180007200 ⚠
RNA-binding protein 29 - putative
— OG7
LINF_180016500 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LINF_040008400 ⚠
mitochondrial exoribonuclease DSS-1 - putativ
— OG7
LINF_160017100 ⚠
WW domain containing protein - putative
— OG7
LINF_320023600 ⚠
hypothetical protein - conserved
— OG7
LINF_350028700 ⚠
poly(A)-specific ribonuclease PARN - putative
— OG7
LINF_180016400 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LINF_260019200 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LINF_340018100 ⚠
Dihydrouridine synthase (Dus) - putative
— OG7
LINF_350048400 ⚠
predicted zinc finger protein
— OG7
LINF_260010800 ⚠
Protein of unknown function (DUF525) - putati
— OG7
LINF_290016900 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LINF_180018600 ⚠
cholinephosphate cytidylyltransferase A - put
— OG7
LINF_230008300 ⚠
tryptophanyl-tRNA synthetase - putative
— OG7
LINF_290027300 ⚠
hypothetical protein - conserved
— OG7
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_030009600 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LINF_190015000 ⚠
FYVE zinc finger containing protein - putativ
— OG7
LINF_210006900 ⚠
serine/threonine-protein kinase-like protein
— OG7
LINF_350058700 ⚠
ribosome-interacting GTPase 2 - putative
— OG7
LINF_180011700 ⚠
serine/threonine kinase-like protein - putati
— OG7
LINF_070015200 ⚠
serine/threonine kinase - putative
— OG7
LINF_300033700 ⚠
GTPase activator-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.