LINF_350029800

ubiquitin-protein ligase - putative
Leishmania infantum JPCM5 OG6: OG6_146796 OG7: OG7_0002947 164 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 164 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_160009000 ⚠
XRN 5'-3' exonuclease N-terminus - putative
— OG7
LINF_360078900 ⚠
ATPase - putative
— OG7
LINF_200016000 ⚠
hypothetical protein - conserved
— OG7
LINF_300028100 ⚠
Leucine Rich repeats (2 copies) - putative
— OG7
LINF_230010200 ⚠
SNF1-related protein kinase regulatory subuni
— OG7
LINF_300016500 ⚠
WW domain containing protein - putative
— OG7
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_300014700 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_070008000 ⚠
ubiquitin-protein ligase-like - putative
— OG7
LINF_160017100 ⚠
WW domain containing protein - putative
— OG7
LINF_180018500 ⚠
hypothetical protein - conserved
— OG7
LINF_300012500 ⚠
co-chaperone GrpE - putative
— OG7
LINF_300012600 ⚠
heat shock protein grpe
— OG7
LINF_330033100 ⚠
ras-like small GTPases - putative
— OG7
LINF_350057700 ⚠
GTP-binding protein - putative
— OG7
LINF_050009600 ⚠
GTPase - putative
— OG7
LINF_260018700 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LINF_230008400 ⚠
hypothetical protein - conserved
— OG7
LINF_360049400 ⚠
zinc carboxypeptidase - putative
— OG7
LINF_080008000 ⚠
Isochorismatase family - putative
— OG7
LINF_330007100 ⚠
metallo-peptidase - Clan MC - Family M14 - pu
— OG7
LINF_080008100 ⚠
Isochorismatase family - putative
— OG7
LINF_120005600 ⚠
ribonuclease mar1
— OG7
LINF_080007200 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LINF_250023700 ⚠
LSM domain containing protein - putative
— OG7
LINF_360049700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_310035800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_010006500 ⚠
LSM domain containing protein - putative
— OG7
LINF_010012200 ⚠
ubiquitin activating enzyme - putative
— OG7
LINF_320016400 ⚠
small nuclear ribonucleoprotein - putative
— OG7
LINF_350050400 ⚠
sm-f snRNP core complex protein - putative
— OG7
LINF_360033800 ⚠
cyclin-e binding protein 1-like protein
— OG7
LINF_300017700 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LINF_260005000 ⚠
Lsm7p protein - putative
— OG7
LINF_260012400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_110009100 ⚠
chromatin binding protein - putative
— OG7
LINF_170008700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_260012500 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_150020800 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_350022300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_190015800 ⚠
hypothetical protein - conserved
— OG7
LINF_030009200 ⚠
TLD domain protein - conserved
— OG7
LINF_090018300 ⚠
hypothetical protein - conserved
— OG7
LINF_300010700 ⚠
hypothetical protein - conserved
— OG7
LINF_320016100 ⚠
hypothetical protein - conserved
— OG7
LINF_360026200 ⚠
TLD - putative
— OG7
LINF_060015100 ⚠
TLD - putative
— OG7
LINF_300039300 ⚠
calmodulin-related protein - putative
— OG7
LINF_090019400 ⚠
Zinc finger- C3HC4 type (RING finger) contai
— OG7
LINF_090016800 ⚠
hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.