LINF_010012200

ubiquitin activating enzyme - putative
Leishmania infantum JPCM5 OG6: OG6_101845 OG7: OG7_0003569 124 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 124 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— OG7
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— OG7
LINF_080009200 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_300010700 ⚠
hypothetical protein - conserved
— OG7
LINF_330027700 ⚠
ribosome assembly protein RRB1 - putative
— OG7
LINF_050006700 ⚠
dihydrolipoamide branched chain transacylase
— OG7
LINF_300031400 ⚠
replication factor C - subunit 2 - putative
— OG7
LINF_330010500 ⚠
DNA mismatch repair protein MSH2 - putative
— OG7
LINF_320016100 ⚠
hypothetical protein - conserved
— OG7
LINF_180017700 ⚠
prolyl-tRNA synthetase - putative
— OG7
LINF_260005000 ⚠
Lsm7p protein - putative
— OG7
LINF_350037400 ⚠
RNA-binding protein - putative
— OG7
LINF_180010500 ⚠
hypothetical protein - conserved
— OG7
LINF_220011900 ⚠
guide RNA associated protein - GAP2 - putativ
— OG7
LINF_260019700 ⚠
farnesyltransferase beta subunit
— OG7
LINF_110014900 ⚠
PUB domain containing protein - putative
— OG7
LINF_160017100 ⚠
WW domain containing protein - putative
— OG7
LINF_180017600 ⚠
prolyl-tRNA synthetase - putative
— OG7
LINF_360039000 ⚠
hypothetical protein - conserved
— OG7
LINF_350011600 ⚠
vacuolar ATP synthase subunit d - putative
— OG7
LINF_340050700 ⚠
nucleolar protein family a - putative
— OG7
LINF_320014300 ⚠
phenylalanyl-tRNA synthetase alpha chain - pu
— OG7
LINF_090013600 ⚠
ubiquitin ligase - putative
— OG7
LINF_100006500 ⚠
hypothetical protein - conserved
— OG7
LINF_320007200 ⚠
Histone chaperone Rttp106-like - putative
— OG7
LINF_300009700 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_240025100 ⚠
WD domain - G-beta repeat/PFU (PLAA family ub
— OG7
LINF_120007000 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_320036300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_350029400 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_270019200 ⚠
ubiquitin carboxyl-terminal hydrolase - putat
— OG7
LINF_340028800 ⚠
asparaginyl-tRNA synthetase - putative
— OG7
LINF_210016300 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_230020500 ⚠
coronin - putative
— OG7
LINF_250021400 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
LINF_240026400 ⚠
tubulin folding cofactor D - putative
— OG7
LINF_060015100 ⚠
TLD - putative
— OG7
LINF_360026200 ⚠
TLD - putative
— OG7
LINF_100019400 ⚠
hypothetical protein - conserved
— OG7
LINF_260024300 ⚠
hypothetical protein - conserved
— OG7
LINF_230006100 ⚠
GDP-mannose pyrophosphorylase
— OG7
LINF_210027500 ⚠
ATP synthase F1 subunit gamma protein - putat
— OG7
LINF_350019000 ⚠
threonyl-tRNA synthetase - putative
— OG7
LINF_150008200 ⚠
ribonucleoprotein p18 - mitochondrial precurs
— OG7
LINF_360062100 ⚠
AP-3 complex subunit beta - putative
— OG7
LINF_110015900 ⚠
adaptin-related protein-like protein
— OG7
LINF_360079500 ⚠
adaptin complex 1 subunit - putative
— OG7
LINF_030009200 ⚠
TLD domain protein - conserved
— OG7
LINF_150008100 ⚠
ribonucleoprotein p18 - mitochondrial precurs
— OG7
LINF_340048700 ⚠
GRIP domain containing protein - putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.