LINF_030009200

TLD domain protein - conserved
Leishmania infantum JPCM5 OG6: OG6_151258 OG7: OG7_0001911 93 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 93 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_020006400 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— Both
LINF_350050400 ⚠
sm-f snRNP core complex protein - putative
— OG7
LINF_350037900 ⚠
replication factor C - subunit 3 - putative
— OG7
LINF_320016400 ⚠
small nuclear ribonucleoprotein - putative
— OG7
LINF_070008000 ⚠
ubiquitin-protein ligase-like - putative
— OG7
LINF_300009700 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_340047400 ⚠
HECT-domain (ubiquitin-transferase) - putativ
— OG7
LINF_010006500 ⚠
LSM domain containing protein - putative
— OG7
LINF_300012500 ⚠
co-chaperone GrpE - putative
— OG7
LINF_350029800 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_280030900 ⚠
WW domain containing protein - putative
— OG7
LINF_010012200 ⚠
ubiquitin activating enzyme - putative
— OG7
LINF_360053000 ⚠
ubiquitin protein ligase - putative
— OG7
LINF_160017100 ⚠
WW domain containing protein - putative
— Both
LINF_180017600 ⚠
prolyl-tRNA synthetase - putative
— Both
LINF_260017200 ⚠
Leucine rich repeat - putative
— Both
LINF_110014900 ⚠
PUB domain containing protein - putative
— Both
LINF_260005000 ⚠
Lsm7p protein - putative
— Both
LINF_260019700 ⚠
farnesyltransferase beta subunit
— Both
LINF_220011900 ⚠
guide RNA associated protein - GAP2 - putativ
— Both
LINF_350037400 ⚠
RNA-binding protein - putative
— Both
LINF_180010500 ⚠
hypothetical protein - conserved
— Both
LINF_340028800 ⚠
asparaginyl-tRNA synthetase - putative
— Both
LINF_330027700 ⚠
ribosome assembly protein RRB1 - putative
— Both
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_210016300 ⚠
aspartyl-tRNA synthetase - putative
— OG7
LINF_360038000 ⚠
ATP-dependent RNA helicase - putative
— OG7
LINF_190021300 ⚠
eukaryotic translation initiation factor-like
— OG7
LINF_150012400 ⚠
ecotin - putative
— OG7
LINF_300031400 ⚠
replication factor C - subunit 2 - putative
— OG7
LINF_280032200 ⚠
eukaryotic translation initiation factor 4E -
— OG7
LINF_170011700 ⚠
ATPase family associated with various cellula
— OG7
LINF_340048100 ⚠
geranylgeranyltransferase - putative
— OG7
LINF_360075700 ⚠
protein transport protein Sec23-like protein
— OG7
LINF_170018700 ⚠
WW domain containing protein - putative
— OG7
LINF_290011000 ⚠
NF-X1 type zinc finger containing protein - p
— OG7
LINF_320016100 ⚠
hypothetical protein - conserved
— Both
LINF_150008400 ⚠
inhibitor of serine peptidase (ISP) - putativ
— OG7
LINF_250023700 ⚠
LSM domain containing protein - putative
— OG7
LINF_270023100 ⚠
eukaryotic translation initiation factor eIF-
— OG7
LINF_300016500 ⚠
WW domain containing protein - putative
— OG7
LINF_200016000 ⚠
hypothetical protein - conserved
— OG7
LINF_360078900 ⚠
ATPase - putative
— OG7
LINF_320012800 ⚠
Outer row dynein-assembly protein 7
— OG7
LINF_360058300 ⚠
hypothetical protein - conserved
— OG7
LINF_300017700 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LINF_270011500 ⚠
replication factor C - subunit 4 - putative
— OG7
LINF_120007600 ⚠
cysteinyl-tRNA synthetase - putative
— Both
LINF_110015300 ⚠
hypothetical protein - conserved
— Both
LINF_150014000 ⚠
hypothetical protein - conserved
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.