LINF_300012500

co-chaperone GrpE - putative
Leishmania infantum JPCM5 OG6: OG6_100642 OG7: OG7_0004892 131 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 131 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_300032600
small glutamine-rich tetratricopeptide repeat
— OG6
LINF_010012200 ⚠
ubiquitin activating enzyme - putative
— OG7
LINF_300031400 ⚠
replication factor C - subunit 2 - putative
— OG7
LINF_180017600 ⚠
prolyl-tRNA synthetase - putative
— OG7
LINF_350037900 ⚠
replication factor C - subunit 3 - putative
— OG7
LINF_270011500 ⚠
replication factor C - subunit 4 - putative
— OG7
LINF_240015100 ⚠
replication factor C - subunit 1 - putative
— OG7
LINF_360078900 ⚠
ATPase - putative
— OG7
LINF_200016000 ⚠
hypothetical protein - conserved
— OG7
LINF_180018500 ⚠
hypothetical protein - conserved
— OG7
LINF_350033000 ⚠
hypothetical protein - conserved
— OG7
LINF_350029800 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_330031600 ⚠
glycosyl hydrolase-like protein
— OG7
LINF_340047400 ⚠
HECT-domain (ubiquitin-transferase) - putativ
— OG7
LINF_070008000 ⚠
ubiquitin-protein ligase-like - putative
— OG7
LINF_350053700 ⚠
BRCA1 C Terminus (BRCT) domain containing pro
— OG7
LINF_360053000 ⚠
ubiquitin protein ligase - putative
— OG7
LINF_340033600 ⚠
hypothetical protein - conserved
— OG7
LINF_300016500 ⚠
WW domain containing protein - putative
— OG7
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_300014700 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_350013900 ⚠
hypothetical protein - conserved
— OG7
LINF_360058700 ⚠
Calponin homology (CH) domain containing prot
— OG7
LINF_050013100 ⚠
Mitochondrial glycoprotein - putative
— OG7
LINF_320016600 ⚠
HECT-domain (ubiquitin-transferase) - putativ
— OG7
LINF_220020900 ⚠
Mitochondrial glycoprotein - putative
— OG7
LINF_330010500 ⚠
DNA mismatch repair protein MSH2 - putative
— OG7
LINF_320016100 ⚠
hypothetical protein - conserved
— OG7
LINF_330027700 ⚠
ribosome assembly protein RRB1 - putative
— OG7
LINF_350037400 ⚠
RNA-binding protein - putative
— OG7
LINF_160017100 ⚠
WW domain containing protein - putative
— OG7
LINF_080007200 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LINF_250023700 ⚠
LSM domain containing protein - putative
— OG7
LINF_010006500 ⚠
LSM domain containing protein - putative
— OG7
LINF_280024000 ⚠
Putative GTPase activating protein for Arf -
— OG7
LINF_310017600 ⚠
amidohydrolase - putative
— OG7
LINF_150020800 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_110011900 ⚠
aminopeptidase - putative
— OG7
LINF_350022300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_110012000 ⚠
aminopeptidase - putative
— OG7
LINF_300012100 ⚠
nuclear movement protein - putative
— OG7
LINF_320021500 ⚠
Putative GTPase activating protein for Arf -
— OG7
LINF_090018300 ⚠
hypothetical protein - conserved
— OG7
LINF_260017800 ⚠
hypothetical protein - conserved
— OG7
LINF_290032700 ⚠
protein kinase - putative
— OG7
LINF_230008500 ⚠
hypothetical protein - conserved
— OG7
LINF_130012000 ⚠
Putative GTPase activating protein for Arf -
— OG7
LINF_290008300 ⚠
Putative GTPase activating protein for Arf -
— OG7
LINF_300010700 ⚠
hypothetical protein - conserved
— OG7
LINF_180016500 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.