LINF_070006000

metallo-peptidase - Clan ME - Family M16C
Leishmania infantum JPCM5 OG6: OG6_101809 OG7: OG7_0004979 163 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 163 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_210017100 ⚠
Programmed cell death protein 2 - C-terminal
— Both
LINF_340042900 ⚠
Programmed cell death protein 2 - C-terminal
— OG7
LINF_360053000 ⚠
ubiquitin protein ligase - putative
— OG7
LINF_180007200
RNA-binding protein 29 - putative
— Both
LINF_360029600 ⚠
developmentally regulated GTP-binding protein
— Both
LINF_020008600
casein kinase II - alpha chain - putative
— OG6
LINF_360030700
tyrosine aminotransferase
— Both
LINF_130011500
U-box domain containing protein - putative
— Both
LINF_350019800 ⚠
choline/ethanolamine kinase - putative
— Both
LINF_230011500 ⚠
poly(A)-specific ribonuclease PARN - putative
— Both
LINF_360074400 ⚠
poly(A)-specific ribonuclease PARN - putative
— Both
LINF_290016900 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— Both
LINF_030012500
TatD related DNase - putative
— Both
LINF_170021400
otubain cysteine peptidase - Clan CA - family
— Both
LINF_050007200
hydrogenase - putative
— Both
LINF_350036000
hypothetical protein - conserved
— Both
LINF_280007900 ⚠
DIS3-like exonuclease - putative
— OG7
LINF_040008400 ⚠
mitochondrial exoribonuclease DSS-1 - putativ
— OG7
LINF_180018600 ⚠
cholinephosphate cytidylyltransferase A - put
— OG7
LINF_270020760 ⚠
ethanolamine kinase - putative
— OG7
LINF_350058700 ⚠
ribosome-interacting GTPase 2 - putative
— OG7
LINF_210008800 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LINF_130013600 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LINF_330033100 ⚠
ras-like small GTPases - putative
— OG7
LINF_350028700 ⚠
poly(A)-specific ribonuclease PARN - putative
— OG7
LINF_350057700 ⚠
GTP-binding protein - putative
— OG7
LINF_050009600 ⚠
GTPase - putative
— OG7
LINF_260018700 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LINF_360065300 ⚠
aminopeptidase P1 - putative
— OG7
LINF_350018700 ⚠
mitochondrial processing peptidase - beta sub
— OG7
LINF_360006800 ⚠
elongation factor 2
— OG7
LINF_170008700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_260026100 ⚠
hypothetical protein - conserved
— OG7
LINF_150020800 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_090019400 ⚠
Zinc finger- C3HC4 type (RING finger) contai
— OG7
LINF_340047400 ⚠
HECT-domain (ubiquitin-transferase) - putativ
— OG7
LINF_180008700 ⚠
tubulin tyrosine ligase protein - putative
— OG7
LINF_110008900 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LINF_080008100 ⚠
Isochorismatase family - putative
— OG7
LINF_350022300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_360010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LINF_260012400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_230008400 ⚠
hypothetical protein - conserved
— OG7
LINF_170009800 ⚠
Dihydrouridine synthase (Dus) - putative
— OG7
LINF_340018100 ⚠
Dihydrouridine synthase (Dus) - putative
— OG7
LINF_220020900 ⚠
Mitochondrial glycoprotein - putative
— OG7
LINF_110009100 ⚠
chromatin binding protein - putative
— OG7
LINF_050013100 ⚠
Mitochondrial glycoprotein - putative
— OG7
LINF_350054800 ⚠
tubulin tyrosine ligase - putative
— OG7
LINF_360033800 ⚠
cyclin-e binding protein 1-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.