LINF_240027300

3-hydroxy-3-methylglutaryl-CoA synthase - putative
Leishmania infantum JPCM5 OG6: OG6_101064 OG7: OG7_0006553 89 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 89 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_150018800 ⚠
tryparedoxin peroxidase
— Both
LINF_330025600 ⚠
protein kinase - putative
— OG7
LINF_360014700 ⚠
SNF1-related protein kinases - putative
— OG7
LINF_010012900 ⚠
eukaryotic initiation factor 4a - putative
— OG7
LINF_010012800 ⚠
eukaryotic initiation factor 4a - putative
— OG7
LINF_280021300 ⚠
ATP-dependent RNA helicase FAL1 - putative
— OG7
LINF_210006900 ⚠
serine/threonine-protein kinase-like protein
— OG7
LINF_280026600 ⚠
protein kinase - putative
— OG7
LINF_300031000 ⚠
hypothetical protein - conserved
— OG7
LINF_350026800 ⚠
adenine aminohydrolase
— OG7
LINF_150007700 ⚠
sterol carrier protein - putative
— OG7
LINF_200011000
cytidine triphosphate synthase - putative
— Both
LINF_350008800 ⚠
ATP-dependent DEAD-box RNA helicase - putativ
— OG7
LINF_150019000 ⚠
tryparedoxin peroxidase
— Both
LINF_230005400 ⚠
peroxidoxin
— Both
LINF_150018600 ⚠
tryparedoxin peroxidase
— Both
LINF_230014600 ⚠
3-ketoacyl-CoA thiolase - putative
— Both
LINF_320036700 ⚠
nucleoside diphosphate kinase b
— Both
LINF_320036800 ⚠
nucleoside diphosphate kinase b
— Both
LINF_290027200 ⚠
fumarate hydratase - putative
— Both
LINF_240007900 ⚠
fumarate hydratase - putative
— Both
LINF_360044500 ⚠
cysteine synthase
— OG6
LINF_170008800 ⚠
cystathionine beta-synthase
— Both
LINF_280023700 ⚠
NOL1/NOP2/sun family - putative
— OG7
LINF_320028300 ⚠
U5 small nuclear ribonucleoprotein component
— OG7
LINF_250027700 ⚠
elongation factor 2-like protein
— OG7
LINF_320031000 ⚠
NOL1/NOP2/sun family - putative
— OG7
LINF_290031700 ⚠
NLI interacting factor-like phosphatase - put
— OG7
LINF_350031400 ⚠
TFIIF-stimulated CTD phosphatase - putative
— OG7
LINF_250027200 ⚠
NLI interacting factor-like phosphatase - put
— OG7
LINF_350007000 ⚠
NLI interacting factor-like phosphatase - put
— OG7
LINF_360079600 ⚠
nuclear lim interactor-interacting factor - p
— OG7
LINF_310007000 ⚠
nucleolar protein - putative
— OG7
LINF_350040600 ⚠
NLI interacting factor-like phosphatase - put
— OG7
LINF_100015100 ⚠
hypothetical protein - conserved
— Both
LINF_320006000 ⚠
NLI interacting factor-like phosphatase - put
— OG7
LINF_260006500 ⚠
nuclear lim interactor-interacting factor-lik
— OG7
LINF_290027700 ⚠
NOL1/NOP2/sun family - putative
— OG7
LINF_270020760 ⚠
ethanolamine kinase - putative
— OG7
LINF_350028500 ⚠
protein kinase - putative
— OG7
LINF_110007400 ⚠
serine/threonine protein kinase - putative
— OG7
LINF_260008000 ⚠
aminopeptidase-like protein
— OG7
LINF_120016700 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LINF_290027900 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LINF_220014000 ⚠
serine/threonine protein kinase sos2 - putati
— OG7
LINF_100014300
hypothetical protein - conserved
— Both
LINF_070015200 ⚠
serine/threonine kinase - putative
— Both
LINF_180011700 ⚠
serine/threonine kinase-like protein - putati
— Both
LINF_210024300 ⚠
ATP-dependent RNA helicase SUB2 - putative
— Both
LINF_180010100
aconitase - putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.