LINF_190012000

glycosomal malate dehydrogenase
Leishmania infantum JPCM5 OG6: OG6_133291 OG7: OG7_0004751 66 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 66 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_040010800 ⚠
spermidine synthase
— OG7
LINF_060008700 ⚠
serine peptidase - clan SC - family S9A-like
— OG7
LINF_360053800 ⚠
mitochondrial intermediate peptidase - putati
— OG7
LINF_260020700 ⚠
thimet oligopeptidase - putative
— OG7
LINF_130011700 ⚠
Metallopeptidase family M24 - putative
— OG7
LINF_190006400 ⚠
metallo-peptidase - Clan MG - Family M24
— OG7
LINF_200022000 ⚠
amidohydrolase - putative
— OG7
LINF_360079300 ⚠
serine peptidase clan SC - family S9A - putat
— OG7
LINF_200022200 ⚠
amidohydrolase - putative
— OG7
LINF_270033860 ⚠
hypothetical protein (non-ATG)
— OG7
LINF_300019400 ⚠
amidohydrolase - putative
— OG7
LINF_310017700 ⚠
amidohydrolase - putative
— OG7
LINF_090013900 ⚠
oligopeptidase b
— OG7
LINF_140015900 ⚠
sodium/hydrogen exchanger - putative
— OG7
LINF_050008500 ⚠
trypanothione reductase
— OG7
LINF_120015400 ⚠
N-acyl-L-amino acid amidohydrolase
— OG7
LINF_200022100 ⚠
amidohydrolase - putative
— OG7
LINF_220022300 ⚠
ser/thr protein phosphatase - putative
— OG7
LINF_290008000 ⚠
hypothetical protein - conserved
— OG7
LINF_220010800 ⚠
peptidyl-prolyl cis-trans isomerase - putativ
— OG7
LINF_150012400 ⚠
ecotin - putative
— OG7
LINF_150012500 ⚠
ecotin - putative
— OG7
LINF_150008400 ⚠
inhibitor of serine peptidase (ISP) - putativ
— OG7
LINF_360077400 ⚠
y113g7b.23 protein-like protein
— OG7
LINF_290028700 ⚠
Domain of unknown function (DUF4139) - putati
— OG7
LINF_300014900 ⚠
Domain of unknown function (DUF4139) - putati
— OG7
LINF_310017600 ⚠
amidohydrolase - putative
— OG7
LINF_170012100 ⚠
bis(5'-nucleosyl)-tetraphosphatase - symmetri
— OG7
LINF_350008800 ⚠
ATP-dependent DEAD-box RNA helicase - putativ
— OG7
LINF_010012900 ⚠
eukaryotic initiation factor 4a - putative
— OG7
LINF_210024300 ⚠
ATP-dependent RNA helicase SUB2 - putative
— OG7
LINF_010012800 ⚠
eukaryotic initiation factor 4a - putative
— OG7
LINF_280021300 ⚠
ATP-dependent RNA helicase FAL1 - putative
— OG7
LINF_330034400 ⚠
UDP-N-acetylglucosamine pyrophosphorylase - p
— OG7
LINF_140008500 ⚠
threonine synthase - putative
— OG7
LINF_110007600 ⚠
NADH-cytochrome b5 reductase-like protein
— OG7
LINF_360078300 ⚠
2 -3-bisphosphoglycerate-independent phosphog
— OG7
LINF_360037500 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain
— OG7
LINF_300033500 ⚠
chaperonin HSP60/CNP60 - putative
— OG7
LINF_360027100 ⚠
chaperonin HSP60 - mitochondrial precursor
— OG7
LINF_150005400 ⚠
cytochrome-b5 reductase - putative
— OG7
LINF_250028300 ⚠
succinyl-CoA synthetase alpha subunit - putat
— OG7
LINF_360027200 ⚠
chaperonin HSP60 - mitochondrial precursor
— OG7
LINF_240013700 ⚠
triosephosphate isomerase
— OG7
LINF_250028400 ⚠
succinyl-CoA synthetase alpha subunit - putat
— OG7
LINF_300018100 ⚠
pyridoxal kinase - putative
— OG7
LINF_260006300 ⚠
adenine phosphoribosyltransferase
— OG7
LINF_260022200 ⚠
cytochrome c oxidase subunit V - putative
— OG7
LINF_330037900 ⚠
cysteine peptidase - Clan CA - family C51 - p
— OG7
LINF_320024300 ⚠
chaperonin HSP60 - mitochondrial precursor
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.