LINF_050008500

trypanothione reductase
Leishmania infantum JPCM5 OG6: OG6_101659 OG7: OG7_0001626 45 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 45 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_200011000
cytidine triphosphate synthase - putative
— Both
LINF_330030400 ⚠
WD domain - G-beta repeat - putative
— Both
LINF_200022100 ⚠
amidohydrolase - putative
— Both
LINF_120015400 ⚠
N-acyl-L-amino acid amidohydrolase
— Both
LINF_140015900
sodium/hydrogen exchanger - putative
— Both
LINF_090013900 ⚠
oligopeptidase b
— Both
LINF_200022000 ⚠
amidohydrolase - putative
— Both
LINF_340032100 ⚠
ruvB-like DNA helicase - putative
— Both
LINF_270032100 ⚠
TPR-repeat protein - putative
— OG6
LINF_360005700 ⚠
stress-inducible protein STI1 homolog
— OG6
LINF_340006400 ⚠
malate dehydrogenase
— Both
LINF_340006600 ⚠
mitochondrial malate dehydrogenase
— Both
LINF_200022200 ⚠
amidohydrolase - putative
— Both
LINF_340041900 ⚠
ruvb-like 1 DNA helicase - putative
— OG7
LINF_340006300 ⚠
malate dehydrogenase - putative
— OG7
LINF_190012000 ⚠
glycosomal malate dehydrogenase
— OG7
LINF_340006500 ⚠
malate dehydrogenase - putative
— OG7
LINF_310017600 ⚠
amidohydrolase - putative
— OG7
LINF_360079300 ⚠
serine peptidase clan SC - family S9A - putat
— OG7
LINF_300039800 ⚠
WD domain - G-beta repeat - putative
— OG7
LINF_360065300 ⚠
aminopeptidase P1 - putative
— OG7
LINF_120016700 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LINF_260008000 ⚠
aminopeptidase-like protein
— OG7
LINF_290014000
guanine deaminase - putative
— Both
LINF_290028700 ⚠
Domain of unknown function (DUF4139) - putati
— Both
LINF_350038800
6-phosphogluconate dehydrogenase - decarboxyl
— Both
LINF_320036800 ⚠
nucleoside diphosphate kinase b
— Both
LINF_350036100
glycerol kinase - glycosomal - putative
— Both
LINF_260027800
kynureninase - putative
— Both
LINF_240007900 ⚠
fumarate hydratase - putative
— Both
LINF_300041000 ⚠
S-adenosylmethionine synthetase
— Both
LINF_330021300
glutamine aminotransferase - putative
— Both
LINF_050013500
methylthioadenosine phosphorylase - putative
— Both
LINF_230008000
pteridine reductase 1
— Both
LINF_300014900 ⚠
Domain of unknown function (DUF4139) - putati
— Both
LINF_300040800 ⚠
S-adenosylmethionine synthetase
— Both
LINF_290027200 ⚠
fumarate hydratase - putative
— Both
LINF_140018000
enolase
— Both
LINF_350028800 ⚠
aminopeptidase P - putative
— Both
LINF_300037500
3-hydroxy-3-methylglutaryl-CoA reductase
— Both
LINF_320036700 ⚠
nucleoside diphosphate kinase b
— Both
LINF_290030100 ⚠
metallo-peptidase - Clan MA(E) Family M1
— Both
LINF_310017700 ⚠
amidohydrolase - putative
— Both
LINF_300019400 ⚠
amidohydrolase - putative
— Both
LINF_060008700 ⚠
serine peptidase - clan SC - family S9A-like
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.