LINF_300040800

S-adenosylmethionine synthetase
Leishmania infantum JPCM5 OG6: OG6_100388 OG7: OG7_0003674 40 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 40 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_290027200 ⚠
fumarate hydratase - putative
— Both
LINF_150022500 ⚠
glutaminyl-tRNA synthetase - putative
— Both
LINF_140006200 ⚠
inosine-guanine nucleoside hydrolase - putati
— Both
LINF_010009800 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_010010100 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_010010000 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_010010200 ⚠
fatty acyl CoA synthetase 2 - putative
— Both
LINF_240026800 ⚠
transketolase
— Both
LINF_170009800 ⚠
Dihydrouridine synthase (Dus) - putative
— Both
LINF_240007900 ⚠
fumarate hydratase - putative
— Both
LINF_350053100 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— +1 more Both
LINF_120010600 ⚠
glucose-6-phosphate isomerase
— Both
LINF_300038100 ⚠
glutamyl-tRNA synthetase - putative
— OG7
LINF_360010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LINF_310027100 ⚠
dihydrouridine synthase (Dus) - putative
— OG7
LINF_010010400 ⚠
long-chain-fatty-acid-CoA ligase - putative
— OG7
LINF_340018100 ⚠
Dihydrouridine synthase (Dus) - putative
— OG7
LINF_300022900 ⚠
queuine tRNA-ribosyltransferase - putative
— OG7
LINF_280036400 ⚠
heat shock protein 70 - putative
— OG7
LINF_360061300 ⚠
aldehyde dehydrogenase - putative
— OG7
LINF_300036900 ⚠
valyl-tRNA synthetase - putative
— Both
LINF_300034400 ⚠
aldehyde dehydrogenase - putative
— Both
LINF_360030600 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
LINF_300035000 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— Both
LINF_300035200 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— Both
LINF_300035100 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— Both
LINF_110006200 ⚠
NGG1 interacting factor 3-like protein
— Both
LINF_050008500 ⚠
trypanothione reductase
— Both
LINF_270005200 ⚠
Queuine tRNA-ribosyltransferase - putative
— Both
LINF_270015600 ⚠
isovaleryl-coA dehydrogenase - putative
— Both
LINF_130016900 ⚠
adenylosuccinate synthetase - putative
— Both
LINF_290014000 ⚠
guanine deaminase - putative
— Both
LINF_120011500 ⚠
alanine aminotransferase
— Both
LINF_350005400 ⚠
pyruvate kinase
— Both
LINF_350005200 ⚠
pyruvate kinase
— Both
LINF_350005300 ⚠
pyruvate kinase
— Both
LINF_180021400 ⚠
nonspecific nucleoside hydrolase
— Both
LINF_030007100 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_150022600 ⚠
proliferative cell nuclear antigen (PCNA) - p
— Both
LINF_010010300 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.