LINF_270015600

isovaleryl-coA dehydrogenase - putative
Leishmania infantum JPCM5 OG6: OG6_102105 OG7: OG7_0001034 47 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 47 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_150017900
DNA repair protein Rad9 - putative
— OG7
LINF_110016000
pyruvate phosphate dikinase - putative
— Both
LINF_150019000 ⚠
tryparedoxin peroxidase
— Both
LINF_150018800 ⚠
tryparedoxin peroxidase
— Both
LINF_260005300
pyridoxal phosphate containing glycine decarb
— Both
LINF_300024000 ⚠
succinyl-coa:3-ketoacid-coenzyme a transferas
— Both
LINF_360024000
aldehyde dehydrogenase - putative
— Both
LINF_340005700
glucose-6-phosphate 1-dehydrogenase - putativ
— Both
LINF_350005400 ⚠
pyruvate kinase
— Both
LINF_350005200 ⚠
pyruvate kinase
— Both
LINF_350005300 ⚠
pyruvate kinase
— Both
LINF_120010600
glucose-6-phosphate isomerase
— Both
LINF_300040800 ⚠
S-adenosylmethionine synthetase
— Both
LINF_340019200 ⚠
inositol 5-phosphatase-like protein
— OG7
LINF_240013300 ⚠
inositol polyphosphate phosphatase - putative
— OG7
LINF_360017300 ⚠
endonuclease/exonuclease/phosphatase - putati
— OG7
LINF_150019700 ⚠
inositol/phosphatidylinositol phosphatase - p
— OG7
LINF_350048100 ⚠
synaptojanin (N-terminal domain) - putative
— OG7
LINF_300035200 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— OG7
LINF_300038100 ⚠
glutamyl-tRNA synthetase - putative
— OG7
LINF_300035100 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— OG7
LINF_360030600 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
LINF_010010400 ⚠
long-chain-fatty-acid-CoA ligase - putative
— OG7
LINF_300035000 ⚠
glyceraldehyde 3-phosphate dehydrogenase - gl
— OG7
LINF_140006200 ⚠
inosine-guanine nucleoside hydrolase - putati
— Both
LINF_060009000
glutamine synthetase - putative
— Both
LINF_150018600 ⚠
tryparedoxin peroxidase
— Both
LINF_180021400 ⚠
nonspecific nucleoside hydrolase
— Both
LINF_330032400 ⚠
succinyl-coA:3-ketoacid-coenzyme A transferas
— Both
LINF_030007100 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_010010300 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_350053100 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— Both
LINF_320040100
glucosamine-6-phosphate isomerase - putative
— Both
LINF_300024100 ⚠
succinyl-coa:3-ketoacid-coenzyme a transferas
— Both
LINF_340040800
aldose 1-epimerase-like protein
— Both
LINF_150022500 ⚠
glutaminyl-tRNA synthetase - putative
— Both
LINF_340033600
hypothetical protein - conserved
— Both
LINF_010009800 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_230005400 ⚠
peroxidoxin
— Both
LINF_010010100 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_130016900
adenylosuccinate synthetase - putative
— Both
LINF_300041000 ⚠
S-adenosylmethionine synthetase
— Both
LINF_010010000 ⚠
long-chain-fatty-acid-CoA ligase - putative
— Both
LINF_290014000
guanine deaminase - putative
— Both
LINF_010010200 ⚠
fatty acyl CoA synthetase 2 - putative
— Both
LINF_240026800
transketolase
— Both
LINF_230006100
GDP-mannose pyrophosphorylase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.