LINF_320044000

3-hydroxyisobutyryl-coenzyme A hydrolase - putative
Leishmania infantum JPCM5 OG6: OG6_102025 OG7: OG7_0000750 144 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 144 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_160013000 ⚠
transaldolase - putative
— Both
LINF_280026600 ⚠
protein kinase - putative
— OG7
LINF_360011200 ⚠
Elongation factor G1 - mitochondrial - putati
— Both
LINF_350047400 ⚠
Protein of unknown function (DUF2009) - putat
— Both
LINF_270030600 ⚠
protein phosphatase-like protein
— OG6
LINF_350005200 ⚠
pyruvate kinase
— Both
LINF_330005900 ⚠
hypothetical protein - conserved
— Both
LINF_350005300 ⚠
pyruvate kinase
— Both
LINF_010012800 ⚠
eukaryotic initiation factor 4a - putative
— Both
LINF_010012900 ⚠
eukaryotic initiation factor 4a - putative
— Both
LINF_290019000 ⚠
carnitine/choline acetyltransferase - putativ
— Both
LINF_300031200
RNA-binding protein - putative
— OG6
LINF_280019500 ⚠
haloacid dehalogenase-like hydrolase - putati
— Both
LINF_240008500 ⚠
aspartate aminotransferase - putative
— Both
LINF_350012900 ⚠
aspartate aminotransferase - putative
— Both
LINF_320026800 ⚠
Cytidylyltransferase - putative
— Both
LINF_280016800 ⚠
WD domain - G-beta repeat - putative
— Both
LINF_180007900 ⚠
Dephospho-CoA kinase - putative
— Both
LINF_280017100 ⚠
electron-transfer-flavoprotein - alpha polype
— Both
LINF_230025500 ⚠
alanine racemase - putative
— Both
LINF_220008200 ⚠
SEP domain containing protein - putative
— Both
LINF_320014700 ⚠
Alpha/beta hydrolase family - putative
— Both
LINF_340045400 ⚠
phosphomannomutase-like protein
— Both
LINF_340041600 ⚠
amidinotransferase - putative
— Both
LINF_280027300 ⚠
Telomere recombination/Putative GTP-binding c
— Both
LINF_310006400 ⚠
ubiquitin carboxyl-terminal hydrolase - putat
— Both
LINF_010007100
cyclophilin 12 - putative
— OG6
LINF_330017000 ⚠
nicotinate phosphoribosyltransferase - putati
— Both
LINF_330037400 ⚠
transcription elongation factor-like protein
— Both
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— Both
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— Both
LINF_010005200 ⚠
Kinesin-13
— OG7
LINF_130006200 ⚠
Kinesin-13 2
— OG7
LINF_310008200 ⚠
Kinesin-13 4 - putative
— OG7
LINF_130021600 ⚠
Kinesin-13 5 - putative
— OG7
LINF_360045400 ⚠
NUDIX hydrolase 3 - putative
— OG7
LINF_330012100 ⚠
hypothetical protein - conserved
— OG7
LINF_250016200 ⚠
dehydrogenase-like protein
— OG7
LINF_350008800 ⚠
ATP-dependent DEAD-box RNA helicase - putativ
— OG7
LINF_270032300 ⚠
aldo-keto reductase-like protein
— OG7
LINF_310037500 ⚠
aldehyde reductase - putative
— OG7
LINF_340047500 ⚠
AP-1 adapter complex gamma subunit - putative
— OG7
LINF_070005500 ⚠
alpha-adaptin-like protein
— OG7
LINF_300014500 ⚠
adenosine kinase-like protein
— OG7
LINF_190021800 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LINF_220008100 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LINF_220008400 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG7
LINF_170018800 ⚠
5'-3' exoribonuclease B - putative
— OG7
LINF_010007000 ⚠
UBA/TS-N domain/CUE domain/Domain of unknown
— OG7
LINF_280019300 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.