LINF_290018600

Heat shock protein 100 kDa
Leishmania infantum JPCM5 OG6: OG6_100223 OG7: OG7_0002479 171 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 171 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_250027700 ⚠
elongation factor 2-like protein
— Both
LINF_220016300 ⚠
Galactose oxidase - central domain/Kelch moti
— Both
LINF_300030200 ⚠
heat shock 70-related protein 1 - mitochondri
— Both
LINF_300030100 ⚠
heat shock 70-related protein 1 - mitochondri
— Both
LINF_360007100 ⚠
elongation factor 2
— OG7
LINF_360006900 ⚠
elongation factor 2
— OG7
LINF_360006800 ⚠
elongation factor 2
— OG7
LINF_360007000 ⚠
elongation factor 2
— OG7
LINF_300030600 ⚠
heat shock 70-related protein 1 - mitochondri
— Both
LINF_240027100 ⚠
Kelch motif/Galactose oxidase - central domai
— OG7
LINF_240009600 ⚠
Kelch motif/Galactose oxidase - central domai
— OG7
LINF_160005800 ⚠
Galactose oxidase - central domain/Kelch moti
— OG7
LINF_300030000 ⚠
heat shock 70-related protein 1 - mitochondri
— Both
LINF_360020900 ⚠
Kelch motif/Galactose oxidase - central domai
— OG7
LINF_200007100 ⚠
kelch domain-containing protein
— OG7
LINF_280022200 ⚠
Kelch motif/Galactose oxidase - central domai
— OG7
LINF_320028300 ⚠
U5 small nuclear ribonucleoprotein component
— Both
LINF_360071700 ⚠
Galactose oxidase - central domain containing
— OG7
LINF_050013100 ⚠
Mitochondrial glycoprotein - putative
— OG7
LINF_260005000 ⚠
Lsm7p protein - putative
— OG7
LINF_360033800 ⚠
cyclin-e binding protein 1-like protein
— OG7
LINF_330007100 ⚠
metallo-peptidase - Clan MC - Family M14 - pu
— OG7
LINF_360049400 ⚠
zinc carboxypeptidase - putative
— OG7
LINF_250023700 ⚠
LSM domain containing protein - putative
— OG7
LINF_300028100 ⚠
Leucine Rich repeats (2 copies) - putative
— OG7
LINF_310035800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_360049700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_260012500 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_110012000 ⚠
aminopeptidase - putative
— OG7
LINF_360053000 ⚠
ubiquitin protein ligase - putative
— OG7
LINF_250009300 ⚠
Translation initiation factor SUI1 - putative
— Both
LINF_230018400 ⚠
hypothetical protein - conserved
— Both
LINF_270015700 ⚠
XRN 5'-3' exonuclease N-terminus - putative
— Both
LINF_280031900 ⚠
MRP protein-like protein
— OG6
LINF_260009300 ⚠
nucleotide binding protein-like protein
— Both
LINF_210012200 ⚠
nucleotide-binding protein - putative
— Both
LINF_050007500 ⚠
Ankyrin repeat - putative
— Both
LINF_020008600 ⚠
casein kinase II - alpha chain - putative
— OG6
LINF_280024500 ⚠
replication factor A - 51kDa subunit - putati
— Both
LINF_220017200 ⚠
Metallo-beta-lactamase superfamily/Beta-lacta
— Both
LINF_220017300 ⚠
Metallo-beta-lactamase superfamily/Beta-lacta
— Both
LINF_010006500 ⚠
LSM domain containing protein - putative
— OG7
LINF_320016400 ⚠
small nuclear ribonucleoprotein - putative
— OG7
LINF_350022300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_030006400 ⚠
ATP-binding cassette protein subfamily F - me
— OG7
LINF_110011900 ⚠
aminopeptidase - putative
— OG7
LINF_340047400 ⚠
HECT-domain (ubiquitin-transferase) - putativ
— OG7
LINF_170008700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LINF_050007200 ⚠
hydrogenase - putative
— Both
LINF_320027600 ⚠
hypothetical protein - conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.