LINF_220013600 – TrypsnetDB2

LINF_220013600

NADH-cytochrome b5 reductase - putative

Leishmania infantum JPCM5 OG6: OG6_105883 OG7: OG7_0002437 17 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 17 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LINF_190012000 ⚠ glycosomal malate dehydrogenase	—	OG7 Tb927.10.2560 ↔ Tb927.7.2700	OG7
LINF_230016800 ⚠ alcohol dehydrogenase - zinc-containing-like	—	OG7 TCSYLVIO_004057 ↔ TCSYLVIO_004276	OG7
LINF_290016000 ⚠ Alcohol dehydrogenase GroES-like domain/Zinc-	—	OG7 TCSYLVIO_004057 ↔ TCSYLVIO_004276	OG7
LINF_060016300 ⚠ protein disulfide isomerase	—	OG7 TCSYLVIO_003879 ↔ TCSYLVIO_004057	OG7
LINF_260011600 ⚠ protein disulfide isomerase - putative	—	OG7 TCSYLVIO_003879 ↔ TCSYLVIO_004057	OG7
LINF_360081500 ⚠ protein disulfide isomerase 2	—	OG7 TCSYLVIO_003879 ↔ TCSYLVIO_004057	OG7
LINF_060017700 ⚠ Thioredoxin - putative	—	OG7 TCSYLVIO_003879 ↔ TCSYLVIO_004057	OG7
LINF_340027200 ⚠ Thioredoxin/Thioredoxin-like domain/Thioredox	—	OG7 TCSYLVIO_003879 ↔ TCSYLVIO_004057	OG7
LINF_340006500 ⚠ malate dehydrogenase - putative	—	OG7 Tb927.10.2560 ↔ Tb927.7.2700	OG7
LINF_250028300 ⚠ succinyl-CoA synthetase alpha subunit - putat	—	OG6 Tb927.3.2230 ↔ Tb927.7.2700 OG7 Tb927.3.2230 ↔ Tb927.7.2700	Both
LINF_340006300 ⚠ malate dehydrogenase - putative	—	OG7 Tb927.10.2560 ↔ Tb927.7.2700	OG7
LINF_280026200 ⚠ ribose 5-phosphate isomerase - putative	—	OG6 Tb927.11.8970 ↔ Tb927.7.2700 OG7 Tb927.11.8970 ↔ Tb927.7.2700	Both
LINF_240013700 ⚠ triosephosphate isomerase	—	OG6 Tb927.11.5520 ↔ Tb927.7.2700 OG7 Tb927.11.5520 ↔ Tb927.7.2700	Both
LINF_340006600 ⚠ mitochondrial malate dehydrogenase	—	OG6 Tb927.10.2560 ↔ Tb927.7.2700 OG7 Tb927.10.2560 ↔ Tb927.7.2700	Both
LINF_340006400 ⚠ malate dehydrogenase	—	OG6 Tb927.10.2560 ↔ Tb927.7.2700 OG7 Tb927.10.2560 ↔ Tb927.7.2700	Both
LINF_360037500 ⚠ succinyl-CoA ligase [GDP-forming] beta-chain	—	OG6 Tb927.10.7410 ↔ Tb927.7.2700 OG7 Tb927.10.7410 ↔ Tb927.7.2700	Both
LINF_250028400 ⚠ succinyl-CoA synthetase alpha subunit - putat	—	OG6 Tb927.3.2230 ↔ Tb927.7.2700 OG7 Tb927.3.2230 ↔ Tb927.7.2700	Both

Orthogroup expansion — connections between the query proteins

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