LINF_270023300

BRO1-like domain/ALIX V-shaped domain binding to HIV - putative
Leishmania infantum JPCM5 OG6: OG6_102685 OG7: OG7_0003119 18 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 18 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_260008000 ⚠
aminopeptidase-like protein
— Both
LINF_090013900 ⚠
oligopeptidase b
— OG7
LINF_060008700 ⚠
serine peptidase - clan SC - family S9A-like
— OG7
LINF_290030100 ⚠
metallo-peptidase - Clan MA(E) Family M1
— OG7
LINF_120016700 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LINF_220020900 ⚠
Mitochondrial glycoprotein - putative
— OG7
LINF_050013100 ⚠
Mitochondrial glycoprotein - putative
— OG7
LINF_300012600 ⚠
heat shock protein grpe
— OG7
LINF_260025300 ⚠
Methyltransferase domain containing protein -
— OG7
LINF_300030200 ⚠
heat shock 70-related protein 1 - mitochondri
— Both
LINF_290015200 ⚠
5-histidylcysteine sulfoxide synthase - putat
— Both
LINF_230010900
5'-3' exoribonuclease C - putative
— Both
LINF_360079300 ⚠
serine peptidase clan SC - family S9A - putat
— Both
LINF_300030000 ⚠
heat shock 70-related protein 1 - mitochondri
— Both
LINF_300030600 ⚠
heat shock 70-related protein 1 - mitochondri
— Both
LINF_300015300 ⚠
p22 protein precursor - putative
— Both
LINF_300012500 ⚠
co-chaperone GrpE - putative
— Both
LINF_300030100 ⚠
heat shock 70-related protein 1 - mitochondri
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.