LINF_360054300

Protein of unknown function (DUF2870) - putative
Leishmania infantum JPCM5 OG6: OG6_104560 OG7: OG7_0009458 172 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 172 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_070005500 ⚠
alpha-adaptin-like protein
— OG7
LINF_160013000
transaldolase - putative
— Both
LINF_030010500
quinone oxidoreductase - putative
— Both
LINF_060007900 ⚠
5'-3' exoribonuclease A - putative
— Both
LINF_360024300 ⚠
5'-3' exoribonuclease D - putative
— Both
LINF_290019000 ⚠
carnitine/choline acetyltransferase - putativ
— Both
LINF_320016700
exportin 1 - putative
— Both
LINF_300031200
RNA-binding protein - putative
— OG6
LINF_280019500 ⚠
haloacid dehalogenase-like hydrolase - putati
— Both
LINF_240008500 ⚠
aspartate aminotransferase - putative
— Both
LINF_350012900 ⚠
aspartate aminotransferase - putative
— Both
LINF_320026800 ⚠
Cytidylyltransferase - putative
— Both
LINF_280016800
WD domain - G-beta repeat - putative
— Both
LINF_180007900 ⚠
Dephospho-CoA kinase - putative
— Both
LINF_300008800
phosphatase 2C - putative
— OG6
LINF_280017100
electron-transfer-flavoprotein - alpha polype
— Both
LINF_230025500
alanine racemase - putative
— Both
LINF_220008200
SEP domain containing protein - putative
— Both
LINF_320014700
Alpha/beta hydrolase family - putative
— Both
LINF_160005400
Phytanoyl-CoA dioxygenase (PhyH)/2OG-Fe(II) o
— Both
LINF_270030700 ⚠
GTP binding protein - putative
— Both
LINF_340045400
phosphomannomutase-like protein
— Both
LINF_280027300
Telomere recombination/Putative GTP-binding c
— Both
LINF_310006400
ubiquitin carboxyl-terminal hydrolase - putat
— Both
LINF_360071800 ⚠
Sucrase/ferredoxin-like - putative
— Both
LINF_010007100
cyclophilin 12 - putative
— OG6
LINF_280005500
hypothetical protein - conserved
— Both
LINF_330037400 ⚠
transcription elongation factor-like protein
— Both
LINF_340011000
Gamma-soluble NSF attachment protein (SNAP-ga
— Both
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— Both
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— Both
LINF_060016500
deoxyribose-phosphate aldolase - putative
— Both
LINF_010005200 ⚠
Kinesin-13
— OG7
LINF_130006200 ⚠
Kinesin-13 2
— OG7
LINF_310008200 ⚠
Kinesin-13 4 - putative
— OG7
LINF_130021600 ⚠
Kinesin-13 5 - putative
— OG7
LINF_080013100
hypothetical protein - conserved
— OG7
LINF_270025200 ⚠
GTP binding protein - putative
— OG7
LINF_320038700 ⚠
Serine hydrolase (FSH1)/50S ribosome-binding
— OG7
LINF_270032300 ⚠
aldo-keto reductase-like protein
— OG7
LINF_310037500 ⚠
aldehyde reductase - putative
— OG7
LINF_270033890
hypothetical protein - conserved
— OG7
LINF_340047500 ⚠
AP-1 adapter complex gamma subunit - putative
— OG7
LINF_210027200 ⚠
RNA polymerase II - putative
— OG7
LINF_350048400 ⚠
predicted zinc finger protein
— OG7
LINF_280032200 ⚠
eukaryotic translation initiation factor 4E -
— OG7
LINF_220014000 ⚠
serine/threonine protein kinase sos2 - putati
— OG7
LINF_210005500 ⚠
hypothetical protein - conserved
— OG7
LINF_060010700 ⚠
U-box domain containing protein - putative
— OG7
LINF_330025600 ⚠
protein kinase - putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.