LPAL13_030014000

eukaryotic initiation factor 2a, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101220 OG7: OG7_0006220 42 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 42 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_310021800 ⚠
MYND finger containing protein, putative
— OG7
LPAL13_180014100 ⚠
protein kinase A catalytic subunit
— OG6
LPAL13_300017600 ⚠
small nuclear ribonucleoprotein polypeptide e
— Both
LPAL13_260023900
hypothetical protein, conserved
— Both
LPAL13_000016000
eukaryotic translation initiation factor 2 be
— Both
LPAL13_080006200
hypothetical protein, conserved
— Both
LPAL13_340046100 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LPAL13_090016300 ⚠
eukaryotic translation initiation factor 2 su
— Both
LPAL13_230010900
5'-AMP-activated protein kinase beta subunit,
— Both
LPAL13_280010600 ⚠
hypothetical protein, conserved
— Both
LPAL13_130017800
hypothetical protein, conserved
— Both
LPAL13_090007200 ⚠
heat shock protein HslVU, ATPase subunit HslU
— Both
LPAL13_250016600 ⚠
dehydrogenase-like protein
— OG7
LPAL13_150005800 ⚠
heat shock protein HslVU, ATPase subunit HslU
— OG7
LPAL13_000053900 ⚠
LSM domain containing protein, putative
— OG7
LPAL13_090016400 ⚠
eukaryotic translation initiation factor 2 su
— OG7
LPAL13_340050700 ⚠
sm-f snRNP core complex protein, putative
— OG7
LPAL13_320016700 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LPAL13_260005100 ⚠
Lsm7p protein, putative
— OG7
LPAL13_000034700 ⚠
LSM domain containing protein, putative
— OG7
LPAL13_040006600 ⚠
hypothetical protein, conserved
— OG7
LPAL13_180015400 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LPAL13_260023400
deoxyhypusine hydroxylase, putative
— Both
LPAL13_110005900 ⚠
14-3-3 protein, putative
— Both
LPAL13_200055700
serine/threonine protein phosphatase 2A regul
— Both
LPAL13_350011400 ⚠
hypothetical protein
— OG6
LPAL13_350011300 ⚠
CRAL/TRIO domain containing protein, putative
— OG6
LPAL13_180015500 ⚠
Aminoacyl-tRNA editing domain containing prot
— Both
LPAL13_320018800 ⚠
CRAL/TRIO domain containing protein, putative
— OG6
LPAL13_350011200 ⚠
CAP-Gly domain containing protein, putative
— OG6
LPAL13_090011300
cyclin 1, putative
— Both
LPAL13_210011400
phosphoglucomutase, putative
— Both
LPAL13_050015100 ⚠
Methyltransferase domain containing protein,
— Both
LPAL13_350044200
Domain of unknown function (DUF3846)/TPR repe
— OG6
LPAL13_350040600 ⚠
14-3-3 protein-like protein
— Both
LPAL13_300006900 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
LPAL13_300014600 ⚠
adenosine kinase, putative
— Both
LPAL13_200039500 ⚠
adenosine kinase-like protein
— Both
LPAL13_300037600
UV excision repair RAD23-like protein
— Both
LPAL13_330010700
hypothetical protein, conserved
— Both
LPAL13_330036500
guide RNA associated protein, GAP1, putative
— Both
LPAL13_220011100
guide RNA associated protein, GAP2, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.