LPAL13_220011100

guide RNA associated protein, GAP2, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_139815 OG7: OG7_0037740 151 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 151 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_180009400
hypothetical protein, conserved
— Both
LPAL13_330027100
Ribosome assembly protein rrb1, putative
— Both
LPAL13_180016100
hypothetical protein, conserved
— Both
LPAL13_180015400 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LPAL13_180015500 ⚠
Aminoacyl-tRNA editing domain containing prot
— Both
LPAL13_200040300
vacuolar ATP synthase catalytic subunit A, pu
— Both
LPAL13_350020300 ⚠
Zn-finger in Ran binding protein and others,
— OG7
LPAL13_280032200
vacuolar ATP synthase subunit b, putative
— Both
LPAL13_340016000 ⚠
NADH-dependent fumarate reductase, putative
— Both
LPAL13_280018900 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_350051600
paraflagellar rod component, putative
— OG6
LPAL13_200060300 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_280036500 ⚠
heat-shock protein hsp70, putative
— Both
LPAL13_210014900 ⚠
aspartyl-tRNA synthetase, putative
— Both
LPAL13_340034100 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LPAL13_350039300
ATP synthase, putative
— Both
LPAL13_010005200
DNA-damage inducible protein DDI1-like protei
— Both
LPAL13_300008900
kinesin, putative
— OG6
LPAL13_300017800
Zinc finger, C3HC4 type (RING finger) contain
— Both
LPAL13_340016200 ⚠
NADH-dependent fumarate reductase, putative
— Both
LPAL13_000020300 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_030012100 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LPAL13_200006800 ⚠
tRNA pseudouridine synthase, putative
— Both
LPAL13_300037200 ⚠
Ankyrin repeats (3 copies), putative
— OG6
LPAL13_280035900 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_180005800 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— Both
LPAL13_200060500 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_130012600
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
LPAL13_200065700
hypothetical protein, conserved
— Both
LPAL13_330041700 ⚠
Zn-finger in Ran binding protein and others,
— Both
LPAL13_260013100 ⚠
RNA-editing complex protein MP100, putative
— OG7
LPAL13_290024200 ⚠
Domain of unknown function (DUF4379), putativ
— OG7
LPAL13_200058000 ⚠
conserved protein, unknown function
— OG7
LPAL13_010011000 ⚠
ubiquitin activating enzyme, putative
— OG7
LPAL13_000053900 ⚠
LSM domain containing protein, putative
— OG7
LPAL13_340037400 ⚠
replication factor C, subunit 3, putative
— OG7
LPAL13_300017600 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LPAL13_300030300 ⚠
replication factor C, subunit 2, putative
— OG7
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_350078800 ⚠
replication factor C, subunit 5, putative
— OG7
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LPAL13_100006500
hypothetical protein, conserved
— OG7
LPAL13_050013000 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LPAL13_140015700 ⚠
protein kinase, putative
— OG7
LPAL13_350010200 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LPAL13_350051800 ⚠
protein kinase-like protein
— OG7
LPAL13_350005700 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LPAL13_340023000 ⚠
protein kinase-like protein
— OG7
LPAL13_260007900 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LPAL13_260009000 ⚠
pseudouridylate synthase-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.