LPAL13_070008100

ubiquitin-protein ligase-like, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101783 OG7: OG7_0000785 371 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 371 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_260015900 ⚠
Axonemal dynein light chain, putative
— Both
LPAL13_190016400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LPAL13_200051500 ⚠
Midasin, putative
— Both
LPAL13_150016400 ⚠
protein kinase, putative
— Both
LPAL13_240014200 ⚠
dynein arm light chain, putative
— Both
LPAL13_140017100 ⚠
ras-like small GTPases, putative
— OG7
LPAL13_260017300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_260019000 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LPAL13_320008200 ⚠
WD40 repeats, putative
— Both
LPAL13_340040100 ⚠
zinc finger protein, putative
— OG7
LPAL13_330017500 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LPAL13_210016400 ⚠
dynein arm light chain, putative
— Both
LPAL13_340048700 ⚠
predicted zinc finger protein
— OG7
LPAL13_110012500 ⚠
Leucine Rich repeat, putative
— OG7
LPAL13_000053900 ⚠
LSM domain containing protein, putative
— OG7
LPAL13_210009500 ⚠
vacuolar sorting-associated-like protein
— OG7
LPAL13_270019300 ⚠
translation initiation factor eIF2B subunit-l
— OG7
LPAL13_300011100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_220005700 ⚠
transcription factor-like protein
— OG7
LPAL13_350023700 ⚠
neurobeachin/beige protein, putative
— OG7
LPAL13_130018000 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_330008700 ⚠
DNA mismatch repair protein MSH2, putative
— OG7
LPAL13_230008800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_190020800 ⚠
eukaryotic translation initiation factor-like
— OG7
LPAL13_260016900 ⚠
Leucine Rich Repeat/Leucine rich repeat, puta
— OG7
LPAL13_200025600 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LPAL13_200037700 ⚠
zinc finger/Zinc finger domain containing pro
— OG7
LPAL13_310036200 ⚠
acetyl-CoA carboxylase, putative
— OG7
LPAL13_340014200 ⚠
hypothetical protein
— OG7
LPAL13_180016100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_040017300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_000018400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_130008000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LPAL13_230023400 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LPAL13_320020400 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LPAL13_080011600 ⚠
histone deacetylase, putative
— OG7
LPAL13_080009300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_210025600 ⚠
histone deacetylase, putative
— OG7
LPAL13_100013000 ⚠
HEAT repeat, putative
— OG7
LPAL13_130009200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_310036400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_110013600 ⚠
40S ribosomal protein S5
— OG7
LPAL13_110013500 ⚠
Ribosomal protein S7p/S5e, putative
— OG7
LPAL13_010011000 ⚠
ubiquitin activating enzyme, putative
— OG7
LPAL13_060015800 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_100011600 ⚠
Chromatin assembly factor 1 subunit A, putati
— OG7
LPAL13_000018300 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LPAL13_080007000 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LPAL13_300017600 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LPAL13_320016700 ⚠
small nuclear ribonucleoprotein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.