LPAL13_080007000

ubiquitin-activating enzyme-like protein
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101769 OG7: OG7_0003569 139 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 139 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_200060500 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_000020300 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_030010800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200060300 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_200060400 ⚠
hypothetical protein, conserved
— OG6
LPAL13_040010400 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_030013300 ⚠
inorganic pyrophosphatase, putative
— Both
LPAL13_330027100 ⚠
Ribosome assembly protein rrb1, putative
— Both
LPAL13_190005800 ⚠
acidocalcisomal pyrophosphatase
— Both
LPAL13_300011100 ⚠
hypothetical protein, conserved
— Both
LPAL13_080009200 ⚠
WD domain, G-beta repeat, putative
— Both
LPAL13_000053900 ⚠
LSM domain containing protein, putative
— OG7
LPAL13_300013500 ⚠
Armadillo/beta-catenin-like repeats, putative
— Both
LPAL13_330008200 ⚠
heat shock protein 83-17
— +2 more Both
LPAL13_290011700 ⚠
heat shock protein 90, putative
— +2 more Both
LPAL13_150008200 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
LPAL13_010005200 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
LPAL13_240026100 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
LPAL13_320007200 ⚠
Histone chaperone Rttp106-like, putative
— Both
LPAL13_200051800 ⚠
developmentally regulated phosphoprotein-like
— Both
LPAL13_250011900 ⚠
Rab3 GTPase-activating protein catalytic subu
— Both
LPAL13_350039200 ⚠
hypothetical protein, conserved
— Both
LPAL13_350074100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LPAL13_230012400 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LPAL13_260023300 ⚠
hypothetical protein, conserved
— Both
LPAL13_100018300 ⚠
hypothetical protein, conserved
— Both
LPAL13_090012900 ⚠
ubiquitin ligase, putative
— Both
LPAL13_230006000 ⚠
GDP-mannose pyrophosphorylase
— Both
LPAL13_250026100 ⚠
Leucine Rich repeats (2 copies), putative
— Both
LPAL13_340011800 ⚠
vacuolar ATP synthase subunit d, putative
— Both
LPAL13_350051600
paraflagellar rod component, putative
— OG6
LPAL13_240027300 ⚠
tubulin folding cofactor D, putative
— Both
LPAL13_330034700 ⚠
aminopeptidase, putative
— OG7
LPAL13_070013700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LPAL13_350006400 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LPAL13_030012100 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LPAL13_240014000 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LPAL13_150016700 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LPAL13_350017400 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LPAL13_200018100 ⚠
inositol 5-phosphatase-like protein
— OG7
LPAL13_210014900 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_300013000 ⚠
co-chaperone GrpE, putative
— OG7
LPAL13_340029100 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_300016500 ⚠
WW domain containing protein, putative
— OG7
LPAL13_200044100 ⚠
geranylgeranyltransferase, putative
— OG7
LPAL13_100006500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_270020000 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_300010100 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_340028700 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_350062600 ⚠
adaptin, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.