LPAL13_300013000

co-chaperone GrpE, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100642 OG7: OG7_0004892 137 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 137 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_300031400
small glutamine-rich tetratricopeptide repeat
— OG6
LPAL13_300017600 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LPAL13_350078800 ⚠
replication factor C, subunit 5, putative
— OG7
LPAL13_180015400 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LPAL13_240015700 ⚠
replication factor C, subunit 1, putative
— OG7
LPAL13_200059300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_270012200 ⚠
replication factor C, subunit 4, putative
— OG7
LPAL13_170010500 ⚠
ATPase family associated with various cellula
— OG7
LPAL13_000018100 ⚠
Mitochondrial glycoprotein, putative
— OG7
LPAL13_340054400 ⚠
breast cancer carboxy-terminal domain contain
— OG7
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_350058900 ⚠
Calponin homology (CH) domain containing prot
— OG7
LPAL13_200030000 ⚠
hypothetical protein, conserved
— OG7
LPAL13_340014000 ⚠
hypothetical protein, conserved
— OG7
LPAL13_050012400 ⚠
Mitochondrial glycoprotein, putative
— OG7
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LPAL13_320016900 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LPAL13_340032200 ⚠
IQ calmodulin-binding motif containing protei
— OG7
LPAL13_340014100 ⚠
hypothetical protein
— OG7
LPAL13_320016400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_300014800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_330027100 ⚠
Ribosome assembly protein rrb1, putative
— OG7
LPAL13_350053000 ⚠
ubiquitin protein ligase, putative
— OG7
LPAL13_330031500 ⚠
glycosyl hydrolase-like protein
— OG7
LPAL13_160016300 ⚠
WW domain containing protein, putative
— OG7
LPAL13_200043400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LPAL13_340036900 ⚠
RNA-binding protein, putative
— OG7
LPAL13_340029100 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_300016500 ⚠
WW domain containing protein, putative
— OG7
LPAL13_330008700 ⚠
DNA mismatch repair protein MSH2, putative
— OG7
LPAL13_340014200 ⚠
hypothetical protein
— OG7
LPAL13_180016100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_140019600 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
LPAL13_000053900 ⚠
LSM domain containing protein, putative
— OG7
LPAL13_080007000 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LPAL13_290011700 ⚠
heat shock protein 90, putative
— OG7
LPAL13_320022200 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LPAL13_030010800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_330008200 ⚠
heat shock protein 83-17
— OG7
LPAL13_340021800 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_170017300 ⚠
NOL1/NOP2/sun family, putative
— OG7
LPAL13_150017600 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_110010200 ⚠
aminopeptidase, putative
— OG7
LPAL13_130010200 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LPAL13_090016500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_260017500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_290027300 ⚠
protein kinase, putative
— OG7
LPAL13_230008800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_290008400 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LPAL13_300012600 ⚠
nuclear movement protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.