LPAL13_340060500

SPRY domain/HECT-domain (ubiquitin-transferase), putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_158396 OG7: OG7_0000785 360 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 360 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_140017100 ⚠
ras-like small GTPases, putative
— OG7
LPAL13_240014200 ⚠
dynein arm light chain, putative
— OG7
LPAL13_190016400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LPAL13_110012500 ⚠
Leucine Rich repeat, putative
— OG7
LPAL13_330017500 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LPAL13_210016400 ⚠
dynein arm light chain, putative
— OG7
LPAL13_260017300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_340040100 ⚠
zinc finger protein, putative
— OG7
LPAL13_340048700 ⚠
predicted zinc finger protein
— OG7
LPAL13_320008200 ⚠
WD40 repeats, putative
— OG7
LPAL13_260015900 ⚠
Axonemal dynein light chain, putative
— OG7
LPAL13_200051500 ⚠
Midasin, putative
— OG7
LPAL13_260019000 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LPAL13_190005500 ⚠
proteasome alpha 7 subunit, putative
— OG7
LPAL13_300017600 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LPAL13_010011000 ⚠
ubiquitin activating enzyme, putative
— OG7
LPAL13_340050700 ⚠
sm-f snRNP core complex protein, putative
— OG7
LPAL13_320016700 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LPAL13_260005100 ⚠
Lsm7p protein, putative
— OG7
LPAL13_000034700 ⚠
LSM domain containing protein, putative
— OG7
LPAL13_000018400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_210025600 ⚠
histone deacetylase, putative
— OG7
LPAL13_130009200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_100013000 ⚠
HEAT repeat, putative
— OG7
LPAL13_080009300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_080011600 ⚠
histone deacetylase, putative
— OG7
LPAL13_320020400 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LPAL13_230023400 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LPAL13_130008000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LPAL13_170015000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LPAL13_290006400 ⚠
DNA-directed RNA polymerase I-like protein
— OG7
LPAL13_350019500 ⚠
adenylate kinase, putative
— OG7
LPAL13_230022900 ⚠
DNA polymerase zeta catalytic subunit, putati
— OG7
LPAL13_330024800 ⚠
DNA polymerase delta catalytic subunit, putat
— OG7
LPAL13_160020500 ⚠
DNA polymerase I alpha catalytic subunit, put
— OG7
LPAL13_030010800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_190011300 ⚠
intraflagellar transport protein component, p
— OG7
LPAL13_230005700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_210014400 ⚠
Domain of unknown function (DUF4042)/HEAT-lik
— OG7
LPAL13_100006200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_000034500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_270007400 ⚠
proteasome alpha 7 subunit, putative
— OG7
LPAL13_340054800 ⚠
proteasome alpha 1 subunit, putative
— OG7
LPAL13_210024100 ⚠
proteasome alpha 2 subunit, putative
— OG7
LPAL13_140008100 ⚠
proteasome alpha 3 subunit, putative
— OG7
LPAL13_050013900 ⚠
paraflagellar rod protein, putative
— OG7
LPAL13_220011100 ⚠
guide RNA associated protein, GAP2, putative
— OG7
LPAL13_110006100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_190015100 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
LPAL13_350022400 ⚠
proteasome alpha 1 subunit, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.