LPAL13_230023400

DNA polymerase theta (helicase domain only), putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101025 OG7: OG7_0001850 130 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 130 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_340045600 ⚠
U5 snRNA-associated splicing factor
— OG7
LPAL13_280028700 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LPAL13_350038900 ⚠
cullin-like protein
— OG7
LPAL13_160017100 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LPAL13_310036200 ⚠
acetyl-CoA carboxylase, putative
— OG7
LPAL13_240029900 ⚠
cullin-like protein-like protein
— OG7
LPAL13_350031300 ⚠
Cullin protein neddylation domain containing
— OG7
LPAL13_250018600 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LPAL13_050013400 ⚠
CPSF A subunit region containing protein, put
— OG7
LPAL13_350073300 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LPAL13_160018400 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LPAL13_320020000 ⚠
RNA guanylyltransferase, putative
— OG7
LPAL13_230011900 ⚠
hypothetical protein, conserved
— OG7
LPAL13_310006600 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LPAL13_300028300 ⚠
Tetratricopeptide repeats, putative
— OG7
LPAL13_320012800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200043100 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LPAL13_200044700 ⚠
GRIP domain containing protein, putative
— OG7
LPAL13_160016300 ⚠
WW domain containing protein, putative
— OG7
LPAL13_260017300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_230026800 ⚠
neutral sphingomyelinase activation associate
— OG7
LPAL13_200030400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_270015100 ⚠
parallel beta-helix repeat, putative
— OG7
LPAL13_250008200 ⚠
RNA-binding protein, putative
— OG7
LPAL13_190016400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LPAL13_330016700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350066900 ⚠
hypothetical protein, conserved
— OG7
LPAL13_140017100 ⚠
ras-like small GTPases, putative
— OG7
LPAL13_350023700 ⚠
neurobeachin/beige protein, putative
— OG7
LPAL13_250011200 ⚠
RNA polymerase I second largest subunit, puta
— OG7
LPAL13_320034100 ⚠
SpoU rRNA Methylase family, putative
— OG7
LPAL13_160005200 ⚠
AAA domain containing protein, putative
— OG7
LPAL13_300016500 ⚠
WW domain containing protein, putative
— OG7
LPAL13_350079300 ⚠
beta-adaptin, putative
— OG7
LPAL13_340040100 ⚠
zinc finger protein, putative
— OG7
LPAL13_060010600 ⚠
SpoU rRNA Methylase family, putative
— OG7
LPAL13_320018000 ⚠
proteasome regulatory non-ATP-ase subunit, pu
— OG7
LPAL13_340028700 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_320037000 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_020007400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_120006800 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_320009000 ⚠
19S proteasome non-atpase subunit 8
— OG7
LPAL13_320047900 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_030009200 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LPAL13_080009500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_030006400 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LPAL13_330008100 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LPAL13_000036300 ⚠
ABC transport system ATP-binding protein, put
— OG7
LPAL13_250023800 ⚠
elongation factor 2-like protein
— OG7
LPAL13_320029200 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.