LPAL13_140017100

ras-like small GTPases, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_147208 OG7: OG7_0001169 237 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 237 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_110012500 ⚠
Leucine Rich repeat, putative
— OG7
LPAL13_300016500 ⚠
WW domain containing protein, putative
— OG7
LPAL13_160016300 ⚠
WW domain containing protein, putative
— OG7
LPAL13_300014800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_240023600 ⚠
SpoU rRNA Methylase family, putative
— OG7
LPAL13_350079300 ⚠
beta-adaptin, putative
— OG7
LPAL13_300021500 ⚠
CLASP N terminal, putative
— OG7
LPAL13_220005700 ⚠
transcription factor-like protein
— OG7
LPAL13_320034100 ⚠
SpoU rRNA Methylase family, putative
— OG7
LPAL13_300011100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_310008000 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LPAL13_350066900 ⚠
hypothetical protein, conserved
— OG7
LPAL13_330016700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_270015100 ⚠
parallel beta-helix repeat, putative
— OG7
LPAL13_290010000 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LPAL13_200030400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_180015400 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LPAL13_260019500 ⚠
farnesyltransferase beta subunit
— OG7
LPAL13_310020100 ⚠
Leucine Rich repeat, putative
— OG7
LPAL13_310020200 ⚠
hypothetical protein
— OG7
LPAL13_340036900 ⚠
RNA-binding protein, putative
— OG7
LPAL13_210014900 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_200044700 ⚠
GRIP domain containing protein, putative
— OG7
LPAL13_200043100 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LPAL13_320012800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350019800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_300028300 ⚠
Tetratricopeptide repeats, putative
— OG7
LPAL13_350073300 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LPAL13_340029400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_180015500 ⚠
Aminoacyl-tRNA editing domain containing prot
— OG7
LPAL13_000008900 ⚠
hypothetical protein, conserved
— OG7
LPAL13_280021800 ⚠
Cell division control protein 48, putative
— OG7
LPAL13_350029700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200059700 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LPAL13_210014400 ⚠
Domain of unknown function (DUF4042)/HEAT-lik
— OG7
LPAL13_310008100 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LPAL13_310018100 ⚠
Protein of unknown function (DUF3638)/Protein
— OG7
LPAL13_280026800 ⚠
p21-C-terminal region-binding protein, putati
— OG7
LPAL13_040016300 ⚠
adenylate kinase, putative
— OG7
LPAL13_320020000 ⚠
RNA guanylyltransferase, putative
— OG7
LPAL13_160005200 ⚠
AAA domain containing protein, putative
— OG7
LPAL13_350037600 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LPAL13_020005900 ⚠
phosphatidylinositol kinase related protein,
— OG7
LPAL13_350062300 ⚠
glycosyl hydrolase, putative
— OG7
LPAL13_200024600 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
LPAL13_200019700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_310008500 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LPAL13_340032200 ⚠
IQ calmodulin-binding motif containing protei
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.