LPAL13_350029700

hypothetical protein, conserved
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_200213 OG7: OG7_0043554 57 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 57 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_260017300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200030400 ⚠
hypothetical protein, conserved
— Both
LPAL13_350063900 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LPAL13_330027400 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LPAL13_080012300 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LPAL13_300014800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_160016300 ⚠
WW domain containing protein, putative
— OG7
LPAL13_320020400 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LPAL13_230023400 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LPAL13_290006400 ⚠
DNA-directed RNA polymerase I-like protein
— OG7
LPAL13_350019500 ⚠
adenylate kinase, putative
— OG7
LPAL13_040016300 ⚠
adenylate kinase, putative
— OG7
LPAL13_340048700 ⚠
predicted zinc finger protein
— OG7
LPAL13_200044700 ⚠
GRIP domain containing protein, putative
— Both
LPAL13_190016400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LPAL13_140017100 ⚠
ras-like small GTPases, putative
— OG7
LPAL13_320020000 ⚠
RNA guanylyltransferase, putative
— OG7
LPAL13_160005200 ⚠
AAA domain containing protein, putative
— OG7
LPAL13_340040100 ⚠
zinc finger protein, putative
— OG7
LPAL13_270020000 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_340028700 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_320037000 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_050008500 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LPAL13_340040200 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LPAL13_210020100 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LPAL13_000036300 ⚠
ABC transport system ATP-binding protein, put
— OG7
LPAL13_330008100 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LPAL13_120006800 ⚠
ubiquitin hydrolase, putative
— Both
LPAL13_190015100 ⚠
DNA-directed RNA polymerases I and III subuni
— Both
LPAL13_100011600 ⚠
Chromatin assembly factor 1 subunit A, putati
— Both
LPAL13_110006100 ⚠
hypothetical protein, conserved
— Both
LPAL13_330029100 ⚠
mitogen-activated protein kinase, putative
— Both
LPAL13_260019000 ⚠
MORN repeat/FYVE zinc finger containing prote
— Both
LPAL13_310036200 ⚠
acetyl-CoA carboxylase, putative
— Both
LPAL13_100006200 ⚠
hypothetical protein, conserved
— Both
LPAL13_080009300 ⚠
hypothetical protein, conserved
— Both
LPAL13_210019000 ⚠
adenylate kinase, putative
— Both
LPAL13_330016700 ⚠
hypothetical protein, conserved
— Both
LPAL13_060015800 ⚠
WD domain, G-beta repeat, putative
— Both
LPAL13_210025600 ⚠
histone deacetylase, putative
— Both
LPAL13_080011600 ⚠
histone deacetylase, putative
— Both
LPAL13_040017300 ⚠
hypothetical protein, conserved
— Both
LPAL13_030006400 ⚠
ATP-binding cassette protein subfamily F, mem
— Both
LPAL13_130008000 ⚠
ATP-dependent RNA helicase, putative
— Both
LPAL13_170015000 ⚠
ATP-dependent RNA helicase, putative
— Both
LPAL13_300016500 ⚠
WW domain containing protein, putative
— Both
LPAL13_080005000 ⚠
adaptor complex protein (AP) 3 delta subunit
— Both
LPAL13_230011900 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.