LPAL13_310036200

acetyl-CoA carboxylase, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101052 OG7: OG7_0001434 191 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 191 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_080012300 ⚠
phosphoribosylpyrophosphate synthetase
— +5 more Both
LPAL13_000015500 ⚠
ribose-phosphate pyrophosphokinase, putative
— +5 more Both
LPAL13_350063900 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +6 more Both
LPAL13_330027400 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +6 more Both
LPAL13_320020400 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LPAL13_230023400 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LPAL13_200007500 ⚠
RNA polymerase ii largest subunit
— Both
LPAL13_310031800 ⚠
RNA polymerase ii largest subunit
— Both
LPAL13_160018400 ⚠
DNA-directed rna polymerase I largest subunit
— Both
LPAL13_130008000 ⚠
ATP-dependent RNA helicase, putative
— Both
LPAL13_170015000 ⚠
ATP-dependent RNA helicase, putative
— Both
LPAL13_000023700 ⚠
ATPase alpha subunit
— Both
LPAL13_350022400 ⚠
proteasome alpha 1 subunit, putative
— OG7
LPAL13_160017100 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LPAL13_280028700 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LPAL13_350038900 ⚠
cullin-like protein
— OG7
LPAL13_350031300 ⚠
Cullin protein neddylation domain containing
— OG7
LPAL13_240029900 ⚠
cullin-like protein-like protein
— OG7
LPAL13_340044800 ⚠
T-complex protein 1, eta subunit, putative
— OG7
LPAL13_270019900 ⚠
T-complex protein 1, beta subunit, putative
— OG7
LPAL13_100013700
hypothetical protein, conserved
— OG7
LPAL13_350080800 ⚠
T-complex protein 1, theta subunit, putative
— OG7
LPAL13_130020000 ⚠
chaperonin TCP20, putative
— OG7
LPAL13_160016300 ⚠
WW domain containing protein, putative
— OG7
LPAL13_300014800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_310006600 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LPAL13_200048300 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LPAL13_180011100
hypothetical protein, conserved
— Both
LPAL13_070017500
proteasome regulatory non-ATP-ase subunit, pu
— Both
LPAL13_200010900
proteasome regulatory non-ATPase subunit 11,
— Both
LPAL13_210012700
proteasome regulatory non-ATP-ase subunit 5,
— Both
LPAL13_340044600 ⚠
proteasome beta 2 subunit, putative
— Both
LPAL13_320018000
proteasome regulatory non-ATP-ase subunit, pu
— Both
LPAL13_010006300
hypothetical protein, conserved
— Both
LPAL13_250018600 ⚠
Cullin family/Cullin protein neddylation doma
— Both
LPAL13_300016500 ⚠
WW domain containing protein, putative
— Both
LPAL13_230011900
hypothetical protein, conserved
— Both
LPAL13_080005000 ⚠
adaptor complex protein (AP) 3 delta subunit
— Both
LPAL13_300040500
ATP synthase, epsilon chain, putative
— Both
LPAL13_000008900
hypothetical protein, conserved
— Both
LPAL13_270015100
parallel beta-helix repeat, putative
— Both
LPAL13_140008100 ⚠
proteasome alpha 3 subunit, putative
— OG7
LPAL13_050009600 ⚠
ATPase alpha subunit
— Both
LPAL13_300018300
hypothetical protein, conserved
— Both
LPAL13_230006100 ⚠
Beige/BEACH domain containing protein, putati
— Both
LPAL13_310018100
Protein of unknown function (DUF3638)/Protein
— Both
LPAL13_140010800
WD domain, G-beta repeat, putative
— Both
LPAL13_000014800
proteasome regulatory non-ATPase subunit 6, p
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.