LPAL13_350031300

Cullin protein neddylation domain containing protein, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_479037 OG7: OG7_0001577 135 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 135 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_170015000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LPAL13_130008000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LPAL13_230023400 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LPAL13_320020400 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LPAL13_310031800 ⚠
RNA polymerase ii largest subunit
— OG7
LPAL13_340029400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200022600 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350073300 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LPAL13_140018100 ⚠
Ribosomal protein S27a, putative
— OG7
LPAL13_000037100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_320012800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_300028300 ⚠
Tetratricopeptide repeats, putative
— OG7
LPAL13_200043100 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LPAL13_200044700 ⚠
GRIP domain containing protein, putative
— OG7
LPAL13_350036000 ⚠
hypothetical protein, conserved
— OG7
LPAL13_350044100 ⚠
polyubiquitin, putative
— OG7
LPAL13_330036100 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LPAL13_090007400 ⚠
DNA replication licensing factor MCM4, putati
— OG7
LPAL13_260017300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200030400 ⚠
hypothetical protein, conserved
— OG7
LPAL13_270015100 ⚠
parallel beta-helix repeat, putative
— OG7
LPAL13_190016400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LPAL13_340055400 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LPAL13_240014900 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LPAL13_330016700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_250018800 ⚠
hypothetical protein, conserved
— OG7
LPAL13_140017100 ⚠
ras-like small GTPases, putative
— OG7
LPAL13_320034100 ⚠
SpoU rRNA Methylase family, putative
— OG7
LPAL13_330035000 ⚠
hypothetical protein, conserved
— OG7
LPAL13_340040100 ⚠
zinc finger protein, putative
— OG7
LPAL13_350079300 ⚠
beta-adaptin, putative
— OG7
LPAL13_310032300 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LPAL13_060010600 ⚠
SpoU rRNA Methylase family, putative
— OG7
LPAL13_350011600 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LPAL13_050013400 ⚠
CPSF A subunit region containing protein, put
— OG7
LPAL13_310036200 ⚠
acetyl-CoA carboxylase, putative
— OG7
LPAL13_210020100 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LPAL13_230011900 ⚠
hypothetical protein, conserved
— OG7
LPAL13_120009300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_180009600 ⚠
Flagellar-associated PapD-like, putative
— OG7
LPAL13_180011100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_040007100 ⚠
exosome complex exonuclease RRP40, putative
— OG7
LPAL13_050008500 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LPAL13_340040200 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LPAL13_140010800 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_070011100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_110007100 ⚠
pumillio protein 10, putative
— OG7
LPAL13_250008200 ⚠
RNA-binding protein, putative
— OG7
LPAL13_030009200 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LPAL13_080005000 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.