LPAL13_200044700

GRIP domain containing protein, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_147115 OG7: OG7_0043222 240 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 240 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_350062600 ⚠
adaptin, putative
— Both
LPAL13_350079300 ⚠
beta-adaptin, putative
— Both
LPAL13_110013800 ⚠
adaptin-related protein-like protein
— OG7
LPAL13_340028700 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_270020000 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_120006800 ⚠
ubiquitin hydrolase, putative
— Both
LPAL13_320037000 ⚠
ubiquitin hydrolase, putative
— Both
LPAL13_350044000 ⚠
Ubiquitin family, putative
— OG7
LPAL13_200056400 ⚠
tubulin-tyrosine ligase, putative
— OG7
LPAL13_290007700 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LPAL13_270033300 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_340055500 ⚠
tubulin tyrosine ligase, putative
— OG7
LPAL13_240014900 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LPAL13_340055400 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LPAL13_090007400 ⚠
DNA replication licensing factor MCM4, putati
— OG7
LPAL13_330036100 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LPAL13_180008600 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LPAL13_300026700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_280031700 ⚠
DNA replication licensing factor MCM6, putati
— OG7
LPAL13_050007900 ⚠
DNA replication licensing factor MCM8, putati
— OG7
LPAL13_320037500 ⚠
DNA replication licensing factor MCM7, putati
— OG7
LPAL13_030012100 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LPAL13_350006400 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LPAL13_070013700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LPAL13_160016300 ⚠
WW domain containing protein, putative
— OG7
LPAL13_300014800 ⚠
ubiquitin-protein ligase, putative
— OG7
LPAL13_070008100 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_080012300 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LPAL13_330027400 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LPAL13_350011600 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LPAL13_350044100 ⚠
polyubiquitin, putative
— OG7
LPAL13_140018100 ⚠
Ribosomal protein S27a, putative
— OG7
LPAL13_350063900 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LPAL13_350036000
hypothetical protein, conserved
— Both
LPAL13_320006400
Armadillo/beta-catenin-like repeat, putative
— Both
LPAL13_260011900
hypothetical protein, conserved
— Both
LPAL13_310018100
Protein of unknown function (DUF3638)/Protein
— Both
LPAL13_230006100 ⚠
Beige/BEACH domain containing protein, putati
— Both
LPAL13_300018300
hypothetical protein, conserved
— Both
LPAL13_260023300 ⚠
hypothetical protein, conserved
— Both
LPAL13_100018300 ⚠
hypothetical protein, conserved
— Both
LPAL13_350029700 ⚠
hypothetical protein, conserved
— Both
LPAL13_350059200
2OG-Fe(II) oxygenase superfamily, putative
— Both
LPAL13_350051400
WD domain, G-beta repeat/Utp21 specific WD40
— Both
LPAL13_340027000
hypothetical protein, conserved
— Both
LPAL13_350027000
hypothetical protein, conserved
— Both
LPAL13_350029600 ⚠
hypothetical protein, conserved
— Both
LPAL13_340039500
acyl transferase-like protein, putative
— Both
LPAL13_200048300 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.