LPAL13_070013700

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_100250 OG7: OG7_0002306 159 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 159 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_330010300 ⚠
hypothetical protein, conserved
— Both
LPAL13_350051600 ⚠
paraflagellar rod component, putative
— Both
LPAL13_340034100 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LPAL13_350005700 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LPAL13_350010200 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LPAL13_300010000 ⚠
eukaryotic translation initiation factor 4e,
— OG7
LPAL13_240005000 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LPAL13_080007000 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LPAL13_200021900 ⚠
Zeta toxin, putative
— OG7
LPAL13_320014300 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— OG7
LPAL13_330008200 ⚠
heat shock protein 83-17
— OG7
LPAL13_230006000 ⚠
GDP-mannose pyrophosphorylase
— OG7
LPAL13_150016700 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LPAL13_320007200 ⚠
Histone chaperone Rttp106-like, putative
— OG7
LPAL13_270020000 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_300013500 ⚠
Armadillo/beta-catenin-like repeats, putative
— OG7
LPAL13_150006800 ⚠
serine/threonine-protein kinase, putative
— OG7
LPAL13_140013200 ⚠
protein kinase, putative
— OG7
LPAL13_350017400 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LPAL13_250026100 ⚠
Leucine Rich repeats (2 copies), putative
— OG7
LPAL13_180008400 ⚠
ATP12 chaperone protein, putative
— OG7
LPAL13_110013800 ⚠
adaptin-related protein-like protein
— OG7
LPAL13_250005000 ⚠
beta-galactofuranosyltransferase-like protein
— OG7
LPAL13_340023000 ⚠
protein kinase-like protein
— OG7
LPAL13_270023300 ⚠
eukaryotic translation initiation factor eIF-
— OG7
LPAL13_050006800 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
LPAL13_090012900 ⚠
ubiquitin ligase, putative
— OG7
LPAL13_260023300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200018100 ⚠
inositol 5-phosphatase-like protein
— OG7
LPAL13_330032900 ⚠
heat shock protein, putative
— OG7
LPAL13_280033000 ⚠
eukaryotic translation initiation factor 4e,
— OG7
LPAL13_200042700 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LPAL13_230008300 ⚠
pteridine reductase 1
— OG7
LPAL13_340028700 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_010011000 ⚠
ubiquitin activating enzyme, putative
— OG7
LPAL13_100006500 ⚠
hypothetical protein, conserved
— OG7
LPAL13_100007900 ⚠
Exonuclease, putative
— OG7
LPAL13_350031400 ⚠
dipeptidyl-peptidase 8-like serine peptidase,
— OG7
LPAL13_200051800 ⚠
developmentally regulated phosphoprotein-like
— OG7
LPAL13_210024700 ⚠
ATP synthase F1 subunit gamma protein, putati
— OG7
LPAL13_350039200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_320037000 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_330026200 ⚠
dual-specificity protein kinase, putative
— OG7
LPAL13_000022400 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LPAL13_230012400 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LPAL13_340028000 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LPAL13_350074100 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LPAL13_350079300 ⚠
beta-adaptin, putative
— OG7
LPAL13_190020800 ⚠
eukaryotic translation initiation factor-like
— OG7
LPAL13_270020700 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.