LPAL13_230012400

poly(A)-specific ribonuclease PARN, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_102215 OG7: OG7_0005534 193 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 193 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_180013400 ⚠
5-oxoprolinase, putative
— Both
LPAL13_200051800 ⚠
developmentally regulated phosphoprotein-like
— Both
LPAL13_240005000 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
LPAL13_240027300 ⚠
tubulin folding cofactor D, putative
— Both
LPAL13_000018300 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
LPAL13_200025600 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LPAL13_120007400 ⚠
cysteinyl-tRNA synthetase, putative
— Both
LPAL13_210014900 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_300010100 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LPAL13_200042700 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LPAL13_100018300 ⚠
hypothetical protein, conserved
— Both
LPAL13_060009400 ⚠
Fructose-bisphosphate aldolase class-I, putat
— OG7
LPAL13_000007600 ⚠
diphthamide synthesis protein, putative
— OG7
LPAL13_160008100 ⚠
tubulin tyrosine ligase, putative
— OG7
LPAL13_200056400 ⚠
tubulin-tyrosine ligase, putative
— OG7
LPAL13_110006200 ⚠
Domain of unknown function(DUF2779), putative
— OG7
LPAL13_350018500 ⚠
fructose-1,6-bisphosphate aldolase
— OG7
LPAL13_290007700 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LPAL13_270033300 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_340055500 ⚠
tubulin tyrosine ligase, putative
— OG7
LPAL13_180008600 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LPAL13_300026700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_060009500 ⚠
Fructose-bisphosphate aldolase class-I, putat
— OG7
LPAL13_180013800 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LPAL13_000034700 ⚠
LSM domain containing protein, putative
— OG7
LPAL13_320016700 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LPAL13_340050700 ⚠
sm-f snRNP core complex protein, putative
— OG7
LPAL13_300017600 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LPAL13_000053900 ⚠
LSM domain containing protein, putative
— OG7
LPAL13_040008700 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LPAL13_280009900 ⚠
DIS3-like exonuclease, putative
— OG7
LPAL13_200025800 ⚠
Uncharacterized conserved protein H4 (DUF2046
— Both
LPAL13_200044700 ⚠
GRIP domain containing protein, putative
— Both
LPAL13_340019300 ⚠
choline/ethanolamine kinase, putative
— Both
LPAL13_340038500 ⚠
hypothetical protein, conserved
— Both
LPAL13_200046600 ⚠
nucleolar protein family a, putative
— Both
LPAL13_300008900 ⚠
kinesin, putative
— OG6
LPAL13_010005200 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
LPAL13_340016200 ⚠
NADH-dependent fumarate reductase, putative
— Both
LPAL13_000020300 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_340011800 ⚠
vacuolar ATP synthase subunit d, putative
— Both
LPAL13_350030700 ⚠
tyrosine aminotransferase
— Both
LPAL13_190010700 ⚠
C-terminal motor kinesin, putative
— OG6
LPAL13_200060500 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LPAL13_290015500 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— Both
LPAL13_340060500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LPAL13_350029800 ⚠
developmentally regulated GTP-binding protein
— Both
LPAL13_350079300 ⚠
beta-adaptin, putative
— Both
LPAL13_070006000 ⚠
metallo-peptidase, Clan ME, Family M16C
— Both
LPAL13_300011100 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.