LPAL13_280009900

DIS3-like exonuclease, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_102526 OG7: OG7_0002439 237 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 237 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_310017200 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LPAL13_140019200 ⚠
inositol-3-phosphate synthase
— +1 more Both
LPAL13_200065900 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LPAL13_150011300 ⚠
hypothetical protein, conserved
— Both
LPAL13_300019600 ⚠
hypothetical protein
— Both
LPAL13_330020900 ⚠
protein kinase, putative
— OG7
LPAL13_110010200 ⚠
aminopeptidase, putative
— OG7
LPAL13_300019500 ⚠
hypothetical protein
— Both
LPAL13_340052000 ⚠
Cysteine-rich motif following a subset of SET
— +1 more Both
LPAL13_300019400 ⚠
Peptidase family M20/M25/M40, putative
— Both
LPAL13_250014900 ⚠
protein kinase, putative
— +1 more Both
LPAL13_200065800 ⚠
hypothetical protein
— Both
LPAL13_330034700 ⚠
aminopeptidase, putative
— +1 more Both
LPAL13_290011700 ⚠
heat shock protein 90, putative
— OG7
LPAL13_100014600 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LPAL13_190021400 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LPAL13_290017000 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LPAL13_310019300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_000041800 ⚠
phosphopantothenoylcysteine decarboxylase, pu
— OG7
LPAL13_190016300 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LPAL13_280027500 ⚠
protein kinase, putative
— OG7
LPAL13_350029800 ⚠
developmentally regulated GTP-binding protein
— OG7
LPAL13_340040100 ⚠
zinc finger protein, putative
— OG7
LPAL13_070006000 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LPAL13_230008600 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LPAL13_180014400 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LPAL13_140017100 ⚠
ras-like small GTPases, putative
— OG7
LPAL13_300016500 ⚠
WW domain containing protein, putative
— OG7
LPAL13_260010400 ⚠
Protein of unknown function (DUF525), putativ
— OG7
LPAL13_300037200 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LPAL13_190016400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LPAL13_210005200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_210006600 ⚠
serine/threonine-protein kinase-like protein
— OG7
LPAL13_350015000 ⚠
SNF1-related protein kinases, putative
— OG7
LPAL13_260017300 ⚠
hypothetical protein, conserved
— OG7
LPAL13_200020100 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— OG7
LPAL13_230012400 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LPAL13_290015500 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LPAL13_200039000 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LPAL13_210005300 ⚠
ALIX V-shaped domain binding to HIV, putative
— OG7
LPAL13_070014900 ⚠
serine/threonine kinase, putative
— OG7
LPAL13_340035500 ⚠
Hydroxyneurosporene synthase (CrtC), putative
— OG7
LPAL13_340028000 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LPAL13_260019000 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LPAL13_170017300 ⚠
NOL1/NOP2/sun family, putative
— OG7
LPAL13_350020100 ⚠
The ARF-like 2 binding protein BART, putative
— OG7
LPAL13_200017000 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LPAL13_260026800 ⚠
kynureninase, putative
— OG7
LPAL13_300013100 ⚠
heat shock protein grpe
— OG7
LPAL13_330006500 ⚠
Ankyrin repeats (3 copies), putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.