LPAL13_070006000

metallo-peptidase, Clan ME, Family M16C
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101809 OG7: OG7_0004979 153 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 153 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_210015700 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LPAL13_200039000 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LPAL13_320029200 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LPAL13_330035200 ⚠
mitochondrial processing peptidase alpha subu
— Both
LPAL13_320023200
NAD+ synthase, putative
— Both
LPAL13_000014700
casein kinase II, alpha chain, putative
— OG6
LPAL13_130009700
U-box domain containing protein, putative
— Both
LPAL13_350030700
tyrosine aminotransferase
— Both
LPAL13_340019300 ⚠
choline/ethanolamine kinase, putative
— Both
LPAL13_350074100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LPAL13_230012400 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LPAL13_290015500 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— Both
LPAL13_030011600
TatD related DNase, putative
— Both
LPAL13_170020000
otubain cysteine peptidase, Clan CA, family C
— Both
LPAL13_000024500
hydrogenase, putative
— Both
LPAL13_340035500
Hydroxyneurosporene synthase (CrtC), putative
— Both
LPAL13_280009900 ⚠
DIS3-like exonuclease, putative
— OG7
LPAL13_040008700 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LPAL13_180013800 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LPAL13_270021400 ⚠
choline kinase
— OG7
LPAL13_350065500 ⚠
aminopeptidase P1, putative
— OG7
LPAL13_340059600 ⚠
ribosome-interacting GTPase 2, putative
— OG7
LPAL13_130011900 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LPAL13_210008300 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LPAL13_050009200 ⚠
GTPase, putative
— OG7
LPAL13_340028000 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LPAL13_340058600 ⚠
GTP-binding protein, putative
— OG7
LPAL13_260018500 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LPAL13_330033000 ⚠
ras-like small GTPases, putative
— OG7
LPAL13_340018500 ⚠
mitochondrial processing peptidase, beta subu
— OG7
LPAL13_030010800
hypothetical protein, conserved
— OG7
LPAL13_350010000 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LPAL13_000018100 ⚠
Mitochondrial glycoprotein, putative
— OG7
LPAL13_230008700 ⚠
hypothetical protein, conserved
— OG7
LPAL13_310033600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_110006600 ⚠
chromatin binding protein, putative
— OG7
LPAL13_170008400 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LPAL13_300026700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_180008600 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LPAL13_260025100 ⚠
hypothetical protein, conserved
— OG7
LPAL13_110006400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LPAL13_120005600 ⚠
ribonuclease mar1
— OG7
LPAL13_320037200 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LPAL13_200043400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LPAL13_350049600 ⚠
zinc carboxypeptidase, putative
— OG7
LPAL13_090014900 ⚠
UEV domain/Zinc finger, C3HC4 type (RING fing
— OG7
LPAL13_350049800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_170007400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LPAL13_100017600 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LPAL13_040011100 ⚠
palmitoyl acyltransferase 1, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.